Tuberc Respir Dis.  2004 Apr;56(4):374-380.

Transbronchial Needle Aspiration in the Diagnosis of Submucosal and Peribronchial Bronchogenic Carcinoma

• Chung JH
• Choi JE
• Park MS
• Kim YS
• Chang J
• Kim SK
• Kim SK

Abstract

Although exophytic endobronchial lesions can readily be diagnosed by routine forceps biopsy through the fiberoptic bronchoscope, submucosal or peribronchial tumor can be difficult to diagnose. So we evaluated the diagnostic utility of transbronchial needle aspiration (TBNA) through the fiberoptic bronchoscope in patients presenting with endoscopic abnormalities suggestive of submucosal or peribronchial tumor.
PATIENTS AND METHODS
Retrospective review of 120 lung cancer patients who were found to have the lesions suggestive of peribronchial and submucosal tumor during fiberoptic bronchoscopy was performed from Jan. 1994 to Dec. 2002 at Severance Hospital, Yonsei University College of Medicine.
METHODS
Forcep biopsy was positive in 63 cases (52.5%) and TBNA in 91 (75.8%), which was significantly better than forcep biopsy (p=0.001). The combination of forceps biopsy and TBNA was positive in 106 cases (88.3%), which was significantly better than forceps biopsy alone (p=0.0001). The difference of TBNA yield according to cell type or bronchoscopic appearance of lesion was not significant, but it showed the relatively better result in small cell carcinoma.
CONCLUSIONS
We concluded that TBNA significantly increase the yield over forcep biopsy alone in the detection of submucosal or peribronchial bronchogenic carcinoma.

Keyword

Transbronchial needle aspiration; Lung cancer; Peribronchial; Submucosal

MeSH Terms

Biopsy
Bronchoscopes
Bronchoscopy
Carcinoma, Bronchogenic*
Carcinoma, Small Cell
Diagnosis*
Humans
Lung Neoplasms
Needles*
Retrospective Studies
Surgical Instruments