Korean J Cytopathol.
1997 Dec;8(2):109-114.
Effectiveness of Transbronchial Fine Needle Aspiration in
Diagnosing Lung Cancers
- Affiliations
-
- 1Department of Pathology, Asan Medical Center, University of Ulsan, College of Medicine.
Abstract
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Transbronchial fine needle aspiration(TBNA) is one of the cytologic methods in
diagnosing lung cancers. TBNA can be used in cases of hilar, mediastinal or lung
masses adjacent to the bronchi. We analyzed and compaired the findings of 27
cases of TBNA and bronchial washing and brushing(BW/BB) in lung cancers
confirmed by either biopsy or surgical resection between Jun, 1996 and May, 1997
in Asan Medical Center. They were 18 cases of non-small cell carcinomas(eight
squamous cell carcinomas, nine adenocarcinomas, and one large cell undifferentiated
carcinoma), eight cases of small cell carcinomas, and one case of metastatic
hepatocellular carcinoma. The sensitivity of TBNA was 37%(10/27) and false negative
was 63%(17/27). Although the sensitivity of BW/BB was 56%(15/27), it was not
different statistically from that of TBNA(Chi square, p=0.38). Overall sensitivity of
TBNA and BW/BB in this series was 70%(19/27). Forty-seven percent of false
negative TBNA(8/17) were positive in BW/BB. The findings suggest that the addition
of TBNA to the standard BW/BB increases diagnostic yield in cytologic diagnosis of
lung cancer.