Psychiatry Investig.  2015 Jan;12(1):146-149. 10.4306/pi.2015.12.1.146.

A Long Term Effects of a New Onset Psychosis after DBS Treated with Quetiapine in a Patient with Parkinson's Disease

• Piccoli S
• Perini G
• Pizzighello S
• Vestri A
• Ferri G
• Toffanin T
• Follador H
• Martinuzzi A

• KMID: 2316401
• DOI: http://doi.org/10.4306/pi.2015.12.1.146

Abstract

Deep Brain Stimulation represents a therapeutic option for PD patients. In this paper, we present and discuss a case of acute delirium and psychosis manifesting after DBS in a 58-years-old man affected by Parkinson's Disease. We highlight the importance of an exhaustive psychiatric evaluation in candidates for DBS and we underline the severity and non-reversibility of some adverse events associated with the implantation, suggesting the use of Quetiapine in the management of these effects. Acute psychosis may be listed as a potential severe adverse event associated with DBS, even in patients without a clear cut previous history of psychiatric disorders.

Keyword

Behavioural symptoms; Deep brain stimulation; Parkinson's disease; Neuropsychiatry; Neuropsychology; Psychopharmacology

MeSH Terms

Deep Brain Stimulation
Delirium
Humans
Neuropsychiatry
Neuropsychology
Parkinson Disease*
Psychopharmacology
Psychotic Disorders*
Quetiapine Fumarate