- Changes in Epidemiological Trends and Rehabilitation Usage in Neurological Diseases in Korea: Parkinson's Disease
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Yun SJ, Seo HG
- KMID: 2525678
- Brain Neurorehabil.
- 2021 Jul;14(2):e12.
- doi: 10.12786/bn.2021.14.e12
Parkinson's disease (PD) is a neurodegenerative disorder characterized by typical motor symptoms such as resting tremor, bradykinesia, and rigidity, as well as non-motor manifestations, including psychiatric symptoms, autonomic dysfunction, and... -
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- Associated Factors on Quality of Life in Patients with Parkinson's Disease
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Bang YM, Song Y, Yun SJ, Seo HG, Chang WH
- KMID: 2525679
- Brain Neurorehabil.
- 2021 Jul;14(2):e13.
- doi: 10.12786/bn.2021.14.e13
The objective of this study is to investigate the clinical and demographic factors that influence the quality of life in patients with Parkinson's disease (PD). This is a crosssectional observational... -
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- Motor Asymmetry and Interocular Retinal Thickness in Parkinson's Disease
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Baek SU, Kang SY, Kwon S, Park IW, Suh W
- KMID: 2512632
- J Korean Med Sci.
- 2021 Feb;36(6):e50.
- doi: 10.3346/jkms.2021.36.e50
Background: To analyze the relationship between interocular difference of retinal thickness and motor asymmetry in Parkinson's disease (PD). Methods: Prospective case-control series analyzed 62 eyes of 31 patients with PD and... -
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- Impaired Hand Dexterity Function in a Non-human Primate Model with Chronic Parkinson’s Disease
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Seo Jc, Won Jy, Kim Kw, Park Jh, Yeo HG, Kim YG, Baek SH, Lee H, Jeon CY, Choi WS, Lee S, Kim KJ, Park SH, Son Yh, Jeong KJ, Lim KS, Kang P, Lee HY, Son HC, Huh JW, Kim YH, Lee DS, Lee SR, Choi JW, Lee Yj
- KMID: 2508474
- Exp Neurobiol.
- 2020 Oct;29(5):376-388.
- doi: 10.5607/en20040
ymptoms of Parkinson’s disease (PD) caused by loss of dopaminergic neurons are accompanied by movement disorders, including tremors, rigidity, bradykinesia, and akinesia. Non-human primate (NHP) models with PD play an... -
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- KSNR Clinical Consensus Statements: Rehabilitation of Patients with Parkinson's Disease
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KSNR PD Writing Group, Kim DY, Oh HM, Bok SK, Chang WH, Choi Y, Chun MH, Han SJ, Han TR, Jee S, Jung SH, Jung HY, Jung TD, Kim MW, Kim EJ, Kim HS, Kim YH, Kim Y, Kim DY, Kim DY, Kim DK, Ko SH, Ko MH, Lee JK, Lee J, Lee SJ, Lee SG, Lim SH, Oh BM, Paik NJ, Park KD, Park SW, Park GY, Park JH, Park YG, Pyun SB, Ryu B, Seo HG, Shin YI, Sohn MK, Yang SN, Yoo SD, Yoo WK
- KMID: 2504421
- Brain Neurorehabil.
- 2020 Jul;13(2):e17.
- doi: 10.12786/bn.2020.13.e17
Clinical consensus statements (CCSs) aim to improve care for patients with Parkinson's disease (PD) and reduce the variability of rehabilitation methods in clinical practice. A literature search was conducted to... -
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- Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists
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Choi JH, Kim JM, Yang HK, Lee HJ, Shin CM, Jeong SJ, Kim WS, Han JW, Yoon IY, Song YS, Bae YJ
- KMID: 2504364
- J Korean Med Sci.
- 2020 Jul;35(28):e230.
- doi: 10.3346/jkms.2020.35.e230
Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders.... -
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- Subtypes of Sleep Disturbance in Parkinson's Disease Based on the Cross-Culturally Validated Korean Version of Parkinson's Disease Sleep Scale-2
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Yang HJ, Kim HJ, Koh SB, Kim JS, Ahn TB, Cheon SM, Cho JW, Kim YJ, Ma HI, Park MY, Baik JS, Lee PH, Chung SJ, Kim JM, Song IU, Kim JY, Sung YH, Kwon DY, Lee JH, Lee JY, Kim JS, Yun JY, Kim HJ, Hong JY, Kim MJ, Youn J, Kim JS, Oh ES, Yoon WT, You S, Kwon KY, Park HE, Lee SY, Kim Y, Kim HT, Kim SJ
- KMID: 2467786
- J Clin Neurol.
- 2020 Jan;16(1):66-74.
- doi: 10.3988/jcn.2020.16.1.66
BACKGROUND AND PURPOSE: This study aimed to determine the clinimetric properties of the Korean version of Parkinson's Disease Sleep Scale-2 (K-PDSS-2) and whether distinct subtypes of sleep disturbance can be... -
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- A Cortical Substrate for Square-Wave Jerks in Progressive Supranuclear Palsy
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Anagnostou E, Karavasilis E, Potiri I, Constantinides V, Efstathopoulos E, Kapaki E, Potagas C
- KMID: 2467782
- J Clin Neurol.
- 2020 Jan;16(1):37-45.
- doi: 10.3988/jcn.2020.16.1.37
BACKGROUND AND PURPOSE: Square-wave jerks (SWJs) are the most common saccadic intrusion in progressive supranuclear palsy (PSP), but their genesis is uncertain. We aimed to determine the characteristics of SWJs... -
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- Full mouth rehabilitation for a Parkinson's diseases patient with chronic periodontitis: a case report
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Koh ES, Kim JJ, Baik J, Cha HS, Lee JH
- KMID: 2470628
- J Dent Rehabil Appl Sci.
- 2019 Dec;35(4):228-234.
- doi: 10.14368/jdras.2019.35.4.228
Parkinson's disease is a neurological disorder characterized by tremor, bradykinesia, akinesia, postural instability, and muscular rigidity, which is caused by the depletion of neurotransmitters such as dopamine. Cooperative dental treatment... -
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- The Influence of Body Mass Index at Diagnosis on Cognitive Decline in Parkinson's Disease
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Yoo HS, Chung SJ, Lee PH, Sohn YH, Kang SY
- KMID: 2467762
- J Clin Neurol.
- 2019 Oct;15(4):517-526.
- doi: 10.3988/jcn.2019.15.4.517
BACKGROUND AND PURPOSE: Associations between alterations in body mass index (BMI) and cognitive function have been reported in Parkinson's disease (PD). We investigated whether the BMI at a PD diagnosis... -
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- Combined Assessment of Serum Alpha-Synuclein and Rab35 is a Better Biomarker for Parkinson's Disease
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Wang HL, Lu CS, Yeh TH, Shen YM, Weng YH, Huang YZ, Chen RS, Liu YC, Cheng YC, Chang HC, Chen YL, Chen YJ, Lin YW, Hsu CC, Lin HL, Chiu CH, Chiu CC
- KMID: 2467758
- J Clin Neurol.
- 2019 Oct;15(4):488-495.
- doi: 10.3988/jcn.2019.15.4.488
BACKGROUND AND PURPOSE: It is essential to develop a reliable predictive serum biomarker for Parkinson's disease (PD). The accumulation of alpha-synuclein (αSyn) and up-regulated expression of Rab35 participate in the... -
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- Backward Gait is Associated with Motor Symptoms and Fear of Falling in Patients with De Novo Parkinson's Disease
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Kwon KY, Park S, Lee HM, Park YM, Kim J, Kim J, Koh SB
- KMID: 2467756
- J Clin Neurol.
- 2019 Oct;15(4):473-479.
- doi: 10.3988/jcn.2019.15.4.473
BACKGROUND AND PURPOSE: Many previous studies have investigated forward gait (FG), backward gait (BG), and dual-task gait (DG) in patients with Parkinson's disease (PD). However, it remains uncertain whether gait... -
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- Cholesterol Metabolism in the Brain and Its Association with Parkinson's Disease
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Jin U, Park SJ, Park SM
- KMID: 2463711
- Exp Neurobiol.
- 2019 Oct;28(5):554-567.
- doi: 10.5607/en.2019.28.5.554
Parkinson's disease (PD) is the second most progressive neurodegenerative disorder of the aging population after Alzheimer’s disease (AD). Defects in the lysosomal systems and mitochondria have been suspected to cause... -
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- The Impact of Impulsivity on Quality of Life in Early Drug-Naïve Parkinson's Disease Patients
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Ryu DW, Kim JS, Yoo SW, Oh YS, Lee KS
- KMID: 2464635
- J Mov Disord.
- 2019 Sep;12(3):172-176.
- doi: 10.14802/jmd.19004
OBJECTIVE: Impulse control disorders (ICDs) in Parkinson's disease (PD) are mostly related to dopamine replacement therapy (DRT); however, drug-naïve PD patients have also frequently experienced impulsivity. This phenomenon makes clinicians... -
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- Modeling α-Synuclein Propagation with Preformed Fibril Injections
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Chung HK, Ho HA, Pérez-Acuña D, Lee SJ
- KMID: 2464631
- J Mov Disord.
- 2019 Sep;12(3):139-151.
- doi: 10.14802/jmd.19046
The aggregation of α-synuclein (α-syn) has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Postmortem... -
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- Spatiotemporal Gait Parameter Comparison for Parkinson's Disease, Multiple System Atrophy, and Other Parkinsonism Diseases
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Bae CH, Jeong HW, Yun JY, Lee JE, Han SJ
- KMID: 2458563
- Brain Neurorehabil.
- 2019 Sep;12(2):e20.
- doi: 10.12786/bn.2019.12.e20
The aim of this study was to compare and quantify the spatiotemporal and gait parameters obtained by foot pressure analysis during the gait in a group of Parkinson's disease (PD)... -
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- Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources
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Hwang DJ, Kwon KC, Song HK, Kim KS, Jung YS, Hwang DY, Cho JY
- KMID: 2470109
- Lab Anim Res.
- 2019 Aug;35(2):61-69.
- doi: 10.1186/s42826-019-0012-2
MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is commonly used to induce nigrostriatal defects to induce parkinsonism and/or parkinsonian syndrome, to replicate the lesions seen in Parkinson's disease (PD), with use in numerous PD models... -
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- Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends
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Hong N
- KMID: 2470030
- Biomed Eng Lett.
- 2019 Aug;9(3):359-366.
- doi: 10.1007/s13534-019-00115-x
Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. Neuronal degeneration is irreversible process and it is proven to be... -
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- 7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
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Ko YH, Kim SK, Kwon SH, Seo JY, Lee BR, Kim YJ, Hur KH, Kim SY, Lee SY, Jang CG
- KMID: 2455091
- Biomol Ther.
- 2019 Jul;27(4):363-372.
- doi: 10.4062/biomolther.2018.211
Daidzein isolated from soybean (Glycine max) has been widely studied for its antioxidant and anti-inflammatory activities. However, the protective effects of 7,8,4′-trihydroxyisoflavone (THIF), a major metabolite of daidzein, on 6-hydroxydopamine... -
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- Heterogeneous Patterns of Striatal Dopamine Loss in Patients with Young- versus Old-Onset Parkinson's Disease: Impact on Clinical Features
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Chung SJ, Yoo HS, Lee YH, Lee PH, Sohn YH
- KMID: 2449683
- J Mov Disord.
- 2019 May;12(2):113-119.
- doi: 10.14802/jmd.18064
OBJECTIVE: Ample evidence has suggested that age at onset of Parkinson's disease (PD) is associated with heterogeneous clinical features in individuals. We hypothesized that this may be attributed to different... -
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