Obstet Gynecol Sci.  2015 Nov;58(6):537-541. 10.5468/ogs.2015.58.6.537.

Mature oocyte retrieval during laparotomic debulking surgery following random-start controlled ovarian stimulation for fertility preservation in a patient with suspected ovarian cancer

• Kim SK
• Kim MS
• Kim H
• Kim SM
• Lee JR
• Suh CS
• Kim SH

• KMID: 2314075
• DOI: http://doi.org/10.5468/ogs.2015.58.6.537

Abstract

Herein, we report a case of successful mature oocyte retrieval during laparotomy after random-start controlled ovarian stimulation (COS) in a 21-year-old nulliparous woman with suspected recurrent ovarian immature teratoma. The patient had been diagnosed with stage IIIC immature teratoma two years earlier following a staging operation, including right oophorectomy and left ovarian cystectomy. And she had subsequently undergone four rounds of postoperative adjuvant chemotherapy with bleomycin, etoposide, and cisplatin. Approximately two years after the initial surgery, she was strongly suspected of having recurrent ovarian immature teratoma on radiologic follow-up. We performed random-start COS and in vivo oocyte retrieval during laparotomic debulking surgery including left oophorectomy. Eight mature oocytes were successfully retrieved and vitrified for fertility preservation. The final pathologic diagnosis was mature cystic teratoma of the ovary and peritoneal implants consistent with gliomatosis peritonei. This is the first case report in which random-start COS and in vivo oocyte retrieval were performed.

Keyword

Fertility preservation; Laparotomy; Oocyte retrieval; Ovarian neoplasms

MeSH Terms

Bleomycin
Chemotherapy, Adjuvant
Cisplatin
Cystectomy
Diagnosis
Etoposide
Female
Fertility Preservation*
Fertility*
Follow-Up Studies
Humans
Laparotomy
Oocyte Retrieval*
Oocytes*
Ovarian Neoplasms*
Ovariectomy
Ovary
Ovulation Induction*
Teratoma
Young Adult
Bleomycin
Cisplatin
Etoposide

Figure

• 

  Fig. 1 (A) In vivo oocyte retrieval via laparotomy after controlled ovarian stimulation of the cancer-affected ovary. (B) Ex vivo oocyte retrieval from the excised ovary after oophorectomy.

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