Obstet Gynecol Sci.  2014 Jan;57(1):66-69.

Developed diplopia and ptosis due to a nonfunctioning pituitary macroadenoma during pregnancy

• Lee HR
• Song JE
• Lee KY

Abstract

Physiologic pituitary enlargement is common during normal pregnancy. However, symptoms such as diplopia, blurred vision and headache resulting from physiologic pituitary enlargement are very rare during pregnancy. A 39-year-old woman complained of sudden diplopia and left eye ptosis at 33th weeks of gestation. An magnetic resonance imaging (MRI) demonstrated the pituitary enlargement compressing the optic chiasm. Notwithstanding the medication of bromocriptine, her symptoms did not regress during pregnancy. At 5 months after delivery, her symptoms dramatically resolved without any surgery, and her visual acuity was normalized. Her MRI scan also revealed more decreased size of pituitary gland compared to antenatal MRI. We report a case of visual loss due to the physiologic pituitary enlargement of nonfunctioning adenoma during pregnancy, which regressed spontaneously after delivery without any surgery.

Keyword

Diplopia; Pituitary adenoma; Pregnancy; Ptosis

MeSH Terms

Adenoma
Adult
Bromocriptine
Diplopia*
Female
Headache
Humans
Magnetic Resonance Imaging
Optic Chiasm
Pituitary Gland
Pituitary Neoplasms
Pregnancy*
Visual Acuity
Bromocriptine

Figure

• 

  Fig. 1 Pituitary magnetic resonance imaging at pregnancy 34 weeks revealed a large pituitary mass with a height of 1.5 cm and compression of the optic chiasm. Arrows indicate the pituitary mass. (A) Sagittal view. (B) Coronal view.

• 

  Fig. 2 Pituitary magnetic resonance imaging at postpartum 4 months revealed decreased size (1.3×1.1×0.7 cm) of a pituitary mass. Arrows indicate the pituitary mass. (A) Sagittal view. (B) Coronal view.

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