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Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas

Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ

BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing...
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Upregulated Long Noncoding RNA LINC01234 Predicts Unfavorable Prognosis for Colorectal Cancer and Negatively Correlates With KLF6 Expression

Jiang X, Zhu Q, Wu P, Zhou F, Chen J

BACKGROUND: LINC01234, a long noncoding RNA (lncRNA), is overexpressed in several cancers, including colorectal cancer (CRC). We investigated the role of LINC01234 in CRC development and confirmed its correlation with...
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Extrauterine Adenomyoma of the Liver Mimicking a Hepatic Adenoma: A Case Report

Won YJ, Woo JY, Byun J, Hong ME

Extrauterine adenomyoma of the liver is extremely rare. Only a few cases have been reported, and these reports have focused mainly on histopathology. Herein, we report the specific imaging findings...
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Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report

Kong JY, Kim HS, Yeon SC, Park JK, Jeong KS, Hong IH

Tumor incidence in wild mammals is reportedly very low. Wild nutria, a large rodent, is known to carry many infectious diseases, but rarely exhibits neoplastic diseases. We necropsied a male...
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Development of Hepatocellular Carcinoma in Patients with Glycogen Storage Disease: a Single Center Retrospective Study

Jang HJ, Yang HR, Ko JS, Moon JS, Chang JY, Seo JK

BACKGROUND: Glycogen storage disease (GSD) is an inherited disorder leading to abnormal glucose metabolism and glycogen accumulation, and is associated with various complications including hepatic adenoma and hepatocellular carcinoma. The...
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Detection of Gastrointestinal Cancer using Linked Color Imaging and Blue Light Imaging

Yoo IK, Cho JY, Osawa H

The early detection of early gastric cancer (EGC) is important. However, the sensitivity of conventional white light imaging (WLI) in detecting EGC had been reported to range only from 77%...
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Impact of Bladder Neck Stiffness on Lower Urinary Tract Symptoms in Patient With Benign Prostatic Hyperplasia

Kwon JK, Jung HD, Cho KS

PURPOSE: We evaluated the impact of bladder neck stiffness on lower urinary tract symptoms in the patient with benign prostatic hyperplasia using elastography. MATERIALS AND METHODS: A total of 384 patients...
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Molecular Mechanisms of Primary Aldosteronism

Tevosian S, Fox SC, Ghayee HK

Primary aldosteronism (PA) results from excess production of mineralocorticoid hormone aldosterone by the adrenal cortex. It is normally caused either by unilateral aldosterone-producing adenoma (APA) or by bilateral aldosterone excess...
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Changing Trends in Preoperative Localization and Surgical Techniques for the Treatment of Primary Hyperparathyroidism in a Single Tertiary Center

Lee J, Kim SJ, Yu HW, Chai YJ, Choi JY, Lee KE

PURPOSE: Primary hyperparathyroidism (PHPT) is caused by the oversecretion of parathyroid hormone (PTH), resulting in increased serum calcium levels. The aim of this study was to analyze changing trends in...
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Validation of an automated adenoma detection rate calculating system for quality improvement of colonoscopy

Sohn DK, Shin IW, Yeon J, Yoo J, Kim BC, Kim B, Hong CW, Han KS

PURPOSE: This study aimed to validate an automated calculating system developed for determining the adenoma detection rate (ADR). METHODS: To calculate the automated ADR, the data linking processes were as follows:...
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A Case of Oncocytic Lipoadenoma Arising in the Submandibular Gland

Lee BS, Lee JK, Jang SK, Seo KH, Kim JH, Bang H, Lee DJ

Oncocytic lipoadenoma is a rare salivary gland tumor composed of adipose tissue and oncocytic epithelial cells in varied proportions. We report a case of an oncocytic lipoadenoma of the submandibular...
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Adrenal Incidentaloma: Imaging Approach and Differential Diagnosis

Lee MS, Moon MH, Sung CK

Adrenal incidentaloma refers to adrenal masses that are accidentally found on imaging performed for other reasons, without clinical symptoms of adrenal disease. Generally, adrenal masses measuring less than 1 cm...
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Incidental Solid Renal Masses: Radiologic Assessment and Managements

Kim DW, Kim SH

The steady increase in imaging studies has led to the incidental discovery of many renal masses. Although most incidental solid renal masses are asymptomatic and small in size, they are...
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A rare case of gastric-type mucinous adenocarcinoma in a woman with Peutz-Jeghers syndrome

Kim Y, Kim EY, Kim TJ, Lim KT, Lee KH, Chun Y, So KA

Adenocarcinoma of the cervix is less common than squamous cell carcinoma. Minimal deviation adenocarcinoma (adenoma malignum) is considered an extremely well-differentiated variant of GAS. An association exists between GAS and...
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A Case of Mucoepidermoid Carcinoma Mixed with Osteosarcoma of the Parotid Gland Extending to the Parapharyngeal Space

Kwon HK, Shin SC, Lee JC, Lee BJ

Carcinosarcomas, also known as true malignant mixed tumors, are rare tumors of the salivary gland and are composed of both malignant epithelial and malignant mesenchymal elements. They may occur in...
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Nomogram Development and External Validation for Predicting the Risk of Lymph Node Metastasis in T1 Colorectal Cancer

Oh JR, Park B, Lee S, Han KS, Youk EG, Lee DH, Kim DS, Lee DS, Hong CW, Kim BC, Kim B, Kim MJ, Park SC, Sohn DK, Chang HJ, Oh JH

PURPOSE: Predicting lymph node metastasis (LNM) risk is crucial in determining further treatment strategies following endoscopic resection of T1 colorectal cancer (CRC). This study aimed to establish a new prediction...
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What Is Appropriate Upper Endoscopic Interval Among Dyspeptic Patients With Previously Normal Endoscopy? A Multicenter Study With Bayesian Change Point Analysis

Kim JW, Jung KW, Kwon JG, Lee JB, Park JK, Bang KB, Tae CH, Oh JH

  • KMID: 2460484
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):544-550.
  • doi: 10.5056/jnm19063
BACKGROUND/AIMS: Appropriate interval for performing follow-up endoscopy among dyspeptic patients without abnormal findings on previous endoscopy is unclear. We analyzed the multicenter-collected data from the Korean Society of Neurogastroenterology and...
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Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line

Lim JS, Eom YW, Lee ES, Kwon HJ, Kwon JY, Choi J, Chung CH, Jo YS, Lee EJ

BACKGROUND: Oxytocin (OXT) has been reported to act as a growth regulator in various tumor cells. However, there is a paucity of data on the influence of OXT on cell...
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Age at menarche and risk of colorectal adenoma

Kim NH, Park JH, Park DI, Sohn CI, Choi K, Jung YS

BACKGROUND/AIMS: Limited data are available regarding the association between age at menarche and the risk of colorectal adenoma. Therefore, we aimed to evaluate the relationship between reproductive factors including age...
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Association between Colorectal Adenoma and Hand Grip Strength in the Elderly

Moon JH, Kim YJ, Oh YH, Kong MH, Kim HJ

BACKGROUND: Obesity is known as an important risk factor for colorectal adenoma. However, for the elderly with changes in body composition, reduced muscle, and increased fat, the body mass index...
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