Incidence of Proximal Colon Adenoma According to Distal Colon Adenoma Characteristics

Hong, Chang Kwon; Lee, June Sung; Kwon, Chang Il; Kim, Kyung Chul; Hong, Sung Pyo; Hwang, Seong Gyu; Park, Pil Won; Lim, Kyu Sung

Abstract

BACKGROUND/AIMS
The aim of this study was to examine the incidence of proximal colon adenoma according to characteristics of distal colon adenoma.
METHODS
Ninety-two colon adenoma patients who underwent total colonoscopy and endoscopic polypectomy were analyzed retrospectively. Adenoma was classified as proximal when located in proximal to splenic flexure. The advanced adenoma was defined as an adenoma larger than 10 mm or any size with a villous component or severe dysplasia.
RESULTS
The incidence of proximal adenoma was increased significantly in those with old age (odds ratio (OR)=3.3), villous (OR=5.3) or dysplastic histology (OR=8.1) or the presence of advanced distal adenoma (OR=3.4). However, the incidence of advanced proximal adenoma was increased only in those with old age (OR=11.2). Nineteen in thirty-nine (48.7%) patients with proximal colon adenoma did not have distal colon adenoma.
CONCLUSIONS
Various characteristics of distal colon adenoma couldn't exactly predict the presence of synchronous proximal adenoma and a greater percentage of subjects with proximal adenoma didn't have distal adenoma. So, colonoscopy could be a standard method for colon cancer screening in Korea.