Lab Anim Res.  2010 Jun;26(2):127-132. 10.5625/lar.2010.26.2.127.

Skin Whitening Effects of Sanguisorba officinalis and Stichopus japonicus

• Lee MO
• Oh HG
• Park SH
• Lee HA
• Sul JD
• Song J
• Kim O

• KMID: 2312057
• DOI: http://doi.org/10.5625/lar.2010.26.2.127

Abstract

This study is aimed to evaluate skin whitening effects of Sanguisorba officinalis and Stichopus japonicus for cosmeceutical ingredients. The extract of Stichopus japonicus showed 61.78% inhibition of tyrosinase activity, and the mixture of Sanguisorba officinalis extract and Stichopus japonicus extract showed 59.14% inhibition of tyrosinase activity. On the clone M-3 cell meloanocyte, the mixture of Sanguisorba officinalis extract and Stichopus japonicus extract showed remarkable inhibition of melanogenesis. Also, those extracts were not irritable in ocular irritation test. It is concluded from these results that Sanguisorba officinalis and Stichopus japonicus have skin whitening effect. It could be used as natural depigmental material in cosmeceutical ingredients.

Keyword

Sanguisorba officinalis; Stichopus japonicus; herb; skin whitening; depigment; cosmeceutical ingredient

MeSH Terms

Clone Cells
Monophenol Monooxygenase
Sanguisorba
Skin
Stichopus
Monophenol Monooxygenase

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