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Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of Phellinus vaninii

Im KH, Baek SA, Choi J, Lee TS

In this study, the antioxidant, anti-xanthine oxidase, anti-melanogenic and anti-wrinkle effects of methanol (ME) and hot water (HE) extracts from the fruiting bodies of Phellinus vaninii were investigated. The 1,1-diphenyl-2-picryl-hydrazyl...
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Anti-melanogenesis and Anti-inflammatory Effects of Cinnamomi Cortex Extract In Vitro

Park JH, Park SJ, Park KY, Kim BJ

  • KMID: 2465952
  • Korean J Dermatol.
  • 2019 Sep;57(8):448-456.
BACKGROUND: Many researchers have sought to identify safe, natural herbal extracts that exert an anti-melanogenesis effect. Cinnamomi cortex has been widely used as a herbal medicine in Asia and Europe. OBJECTIVE:...
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Anti-melanogenic effects of Hordeum vulgare L. barely sprout extract in murine B16F10 melanoma cells

Choi JH, Jung JG, Kim JE, Bang MA

PURPOSE: Barely sprout is a well-known oriental herbal medicine with a wide range of health benefits. Recent studies have provided scientific evidence of its therapeutic effects with expanded application. This...
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Primary Malignant Melanoma of the Breast: A Report of Two Cases

Koh J, Lee J, Jung SY, Kang HS, Yun T, Kwon Y

Primary malignant melanoma of the breast (PMMB) is a rare tumor with only a few case reports available in the literature. We report two cases of PMMB, one derived from...
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Anti-Melanogenic Effect from Submerged Mycelial Cultures of Ganoderma weberianum

Lai YJ, Hsu KD, Huang TJ, Hsieh CW, Chan YH, Cheng KC

Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated the anti-melanogenic activity from the submerged mycelial culture...
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The effects of green tea (Camellia sinensis) flower extracton melanin synthesis in B16-F10 melanoma cells

Dissanayake CY, Moon HH, Yang KM, Lee Y, Han CH

The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited...
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Designing Tyrosinase siRNAs by Multiple Prediction Algorithms and Evaluation of Their Anti-Melanogenic Effects

Kwon OS, Kwon SJ, Kim JS, Lee G, Maeng HJ, Lee J, Hwang GS, Cha HJ, Chun KH

Melanin is a pigment produced from tyrosine in melanocytes. Although melanin has a protective role against UVB radiation-induced damage, it is also associated with the development of melanoma and darker...
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Artemisia capillaris Thunb. inhibits melanin synthesis activity via ERK-dependent MITF pathway in B16/F10 melanoma cells

Saba E, Oh MJ, Lee YY, Kwak D, Kim S, Rhee MH

Genus Artemisia occurs as a hardy plant and has a wide range of culinary and medicinal features. In this study, we aimed to describe the melanin inhibitory activity of one...
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Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway

Ko GA, Shrestha S, Kim Cho S

BACKGROUND/OBJECTIVES: Sageretia thea is traditionally used as a medicinal herb to treat various diseases, including skin disorders, in China and Korea. This study evaluated the inhibitory effect of Sageretia thea...
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Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway

Ko GA, Kim Cho S

Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent....
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Inhibitory effect of Gastrodia elata Blume extract on alpha-melanocyte stimulating hormone-induced melanogenesis in murine B16F10 melanoma

Shim E, Song E, Choi KS, Choi HJ, Hwang J

BACKGROUND/OBJECTIVES: Gastrodia elata Blume (GEB), a traditional herbal medicine, has been used to treat a wide range of neurological disorders (e.g., paralysis and stroke) and skin problems (e.g., atopic dermatitis...
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Pimecrolimus increases the melanogenesis and migration of melanocytes in vitro

Xu P, Chen J, Tan C, Lai RS, Min ZS

Vitiligo is an intriguing depigmentary disorder and is notoriously difficult to be treated. The ultimate goal of vitiligo treatment is to replenish the lost melanocytes by immigration from hair follicle...
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Codon Usage Patterns of Tyrosinase Genes in Clonorchis sinensis

Bae YA

Codon usage bias (CUB) is a unique property of genomes and has contributed to the better understanding of the molecular features and the evolution processes of particular gene. In this...
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Inhibition of Melanogenesis by Abietatriene from Vitex Trifolia Leaf Oil

Lee HG, Kim TY, Jeon JH, Lee SH, Hong YK, Jin MH

Vitex trifolia L. has been used traditionally to treat various illnesses, such as inflammation, headache, migraine, and gastrointestinal infections. We analyzed and evaluated the composition of V. trifolia leaf oil....
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Kojic Acid Peptide: A New Compound with Anti-Tyrosinase Potential

Singh BK, Park SH, Lee HB, Goo YA, Kim HS, Cho SH, Lee JH, Ahn GW, Kim JP, Kang SM, Kim EK

BACKGROUND: Kojic acid was used for decades in the cosmetic industry as an antimelanogenic agent. However, there are two major drawbacks of Kojic acid, one is cytotoxicity and second are...
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Pigmentation Effect of Electromagnetic Fields at Various Intensities to Melanocytes

Cho SE, Kim YM, Kang KH, Kim SC, Park JK, Seo YK

Melanogenesis is the biological process that results in the synthesis of skin pigment of melanin and it has various functions in living systems and is synthesized by the melanosome within...
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Bioassay-Guided Isolation and Identification of Compounds from Arecae Pericarpium with Anti-inflammatory, Anti-oxidative, and Melanogenesis Inhibition Activities

Indriana A, Lee KJ, Kim YS

This study describes the anti-inflammatory, anti-oxidant, and melanogenesis inhibition activities of methanol extract and various organic solvent fractions of Arecae Pericarpium. We examined the inhibition of lipopolysaccharide (LPS)-induced nitric oxide...
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Modulation of Melanin Synthesis by Amaranthus spp. L Seed Extract in Melan-a Cells

Seo JO, Do MH, Lee JH, Lee TH, Wahedi HM, Park YU, Kim SY

Anti-melanogenic effects of amaranth (AT), one of the key source of squalene, were investigated in melanocytes. Amaranth seed powder was extracted with water and melan-a cells were treated with various...
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Chemical Components from the Stems of Pueraria lobata and Their Tyrosinase Inhibitory Activity

Morgan AM, Jeon MN, Jeong MH, Yang SY, Kim YH

Phytochemical investigation of the stems of Pueraria lobata (Wild) Ohwi (Leguminosae), led to the isolation of eighteen known compounds: β-amyrone (1), (+)-pinoresinol (2), (+)-syringaresinol (3) (+)-syringaresinol-O-β-D-glucoside (4), (+)-lariciresinol (5), (-)-tuberosin...
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Biological Activities and Stability of a Standardized Pentacyclic Triterpene Enriched Centella asiatica Extract

Puttarak P, Brantner A, Panichayupakaranant P

Pentacyclic triterpenes, mainly, asiatic acid, madecassic acid, asiaticoside, and madecassoside are the active constituents of Centella asiatica. A pentacyclic triterpene enriched C. asiatica extract (PRE) was prepared and standardized to...
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