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The inhibitory effects of Rheum palmatum extract on the growth of oral streptococci and biofilm formation

Kim SY, Song Y, Lee HA, Na HS, Chung J

Objectives: Oral streptococci play a significant role in the development of dental caries. Among them, Streptococcus mutans and Streptococcus sobrinus are the principal causative agents of dental caries. Rheum palmatum...
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Association Between Gut Regulatory Hormones and Post-operative Weight Loss Following Gastrectomy in Patients With Gastric Cancer

Jung HK, Tae CH, Lee HA, Lee KE, Moon CM, Kim SE, Seoh JY, Lee JH

  • KMID: 2531186
  • J Neurogastroenterol Motil.
  • 2022 Jul;28(3):409-417.
  • doi: 10.5056/jnm21145
Background/Aims Post-operative weight loss in patients with gastric cancer lead to a poor quality of life and long-term survival. This study aims to evaluate the effects of gut regulatory hormones on...
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Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer

Jun H, Lee J, Lee HA, Kim SE, Shim KN, Jung HK, Jung SA, Moon CM

Background/Aims: The relationship between fasting blood glucose (FBG) variability and colorectal cancer (CRC) remains ill-defined. This study aimed to evaluate the association of FBG variability with CRC risk in the...
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Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status

Mun YS, Park HK, Kim J, Yeom J, Kim GH, Chun MY, Lee HA, Yoon SJ, Park KW, Kim EJ, Yoon B, Jang JW, Hong JY, Choi SH, Jeong JH

Background and Purpose: In this study we aimed to find the association between neuropsychological performance and body mass index (BMI) in patients with mild cognitive impairment (MCI). In addition, we...
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Health and Mortality in Korean Healthcare Workers

Shin Y, Kim UJ, Lee HA, Choi EJ, Park HJ, Ahn HS, Park H, Policy Development Committee of NAMOK

Background: To evaluate the health status of healthcare workers (doctors and nurses) compared to those in the general population based on the National Health Insurance Service database and the cause...
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Spontaneous Rupture of Ovarian Artery Aneurysm in a Postmenopausal Woman: A Case Report and Literature Review

Hu YH, Ouh YT, Kim C, Lee SJ, Ahn TG, Lee HA

Spontaneous rupture of an ovarian artery aneurysm is an extremely rare, life-threatening disease and has been reported to be most highly associated with pregnancy. The current study presents a case...
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Serum milk fat globule-EGF factor 8 protein as a potential biomarker for metabolic syndrome

Lee HA, Lim J, Joo HJ, Lee YS, Jung YK, Kim JH, An H, Yim HJ, Jeen YT, Yeon JE, Lim DS, Byun KS, Seo YS

Background/Aims: Useful biomarkers for metabolic syndrome have been insufficient. We investigated the performance of serum milk fat globule-EGF factor-8 (MFG-E8), the key mediator of inflammatory pathway, in diagnosis of metabolic...
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Types of 23S Ribosomal RNA Point Mutations and Therapeutic Outcomes for Helicobacter pylori

Kim SY, Park JM, Lim CH, Lee HA, Shin GY, Choe Y, Cho YK, Choi MG

Background/Aims: Point mutations in the 23S ribosomal RNA gene have been associated with Helicobacter pylori clarithromycin resistance. This study aimed to detect the prevalence of these point mutations and to...
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Direct Bilirubin Is More Valuable than Total Bilirubin for Predicting Prognosis in Patients with Liver Cirrhosis

Lee HA, Jung JY, Lee YS, Jung YK, Kim JH, An H, Yim HJ, Jeen YT, Yeon JE, Byun KS, Um SH, Seo YS

Background/Aims: Most prognostic prediction models for patients with liver cirrhosis include serum total bilirubin (TB) level as a component. This study investigated prognostic performance of serum direct bilirubin (DB) and...
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Small Bowel Necrosis Associated with Catastrophic Antiphospholipid Syndrome: A Case Report

Lee HA, Kim SE, Jung DW, Byeon JR, Choe AR, Tae CH, Moon CM, Jung HK, Shim KN, Jung SA

Catastrophic antiphospholipid syndrome is a highly fatal condition characterized by widespread thromboembolism subsequent to a triggering factor (e.g., infection, trauma, and neoplasia) in antiphospholipid antibody-positive patients. This paper reports a...
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Change in the Recurrence Pattern and Predictors over Time after Complete Cure of Hepatocellular Carcinoma

Lee HA, Lee YS, Kim BK, Jung YK, Kim SU, Park JY, Kim JH, An H, Kim DY, Yim HJ, Ahn SH, Yeon JE, Byun KS, Han KH, Um SH, Seo YS

Background/Aims: We investigated changes in recurrence rates and significant recurrence predictors over time after complete cure of hepatocellular carcinoma (HCC). Methods: A total of 1,491 patients with first-time diagnosis of Barcelona...
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Hepatocellular Carcinoma in Korea: an Analysis of the 2015 Korean Nationwide Cancer Registry

Yoon JS, Lee HA, Kim HY, Sinn DH, Lee DH, Hong SK, Cho JY, Choi J, Chang Y, Kong HJ, Kim E, Won YJ, Lee JH

Background/Aims: Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related death in Korea. This study evaluated the characteristics of Korean patients newly diagnosed...
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Association of Mortality with Antiplatelet Treatment in Patients with Stent Placement or Angioplasty: A Population-Based Nested Case-Control Study

Woo HG, Lee HA, Ryu DR, Song TJ

Purpose: Antiplatelet drugs are essential in patients with cardiovascular disease who undergo stent placement. We hypothesized that risks of mortality would differ according to adherence to antiplatelet agents, number of...
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Comorbidity network analysis related to obesity in middle-aged and older adults: findings from Korean population-based survey data

Lee HA, Park H

OBJECTIVES: We conducted a comorbidity network analysis using data from the seventh Korea National Health and Nutrition Examination Survey to systematically quantify obesity-related comorbidities. METHODS: The study included 11,712 subjects aged...
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Cohort profile: the Ewha Birth and Growth Study

Lee HA, Park B, Min J, Choi EJ, Kim UJ, Park HJ, Park EA, Cho SJ, Kim HS, Lee H, Kim YJ, Hong YS, Kim EJ, Ha EH, Park H

With the introduction of life-course epidemiology, researchers realized the importance of identifying risk factors in early life to prevent chronic diseases. This led to the establishment of the Ewha Birth...
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The Trend and Prospect of Medical Sociology: Its Concepts and the Interface with Medical History

KIM JH, LEE HA

Medical sociology has a long history, and it has been institutionalized and developed since the 1940s. This paper is about the history, trends, and prospects of medical sociology from the...
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Inhibitory effects of Coptis chinensis extract on the growth and biofilm formation of Streptococcus mutans and Streptococcus sobrinus

Kim SY, Song Y, Lee HA, Na HS, Jung CJ, Bek GY, Chung J

Streptococcus mutans and Streptococcus sobrinus play important roles in dental caries. Coptis chinensis is a natural product with antimicrobial activity against enterobacteria; however, its effects on oral streptococci are still...
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Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra

Lee HA, Kim JY, Kim J, Nam B, Kim O

The effect of standard therapeutic strategies on Helicobacter pylori infection is diminished over time owing to the emergence of drug resistant strains. In this study, we would like to confirm...
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Trends in the development of human stem cell-based non-animal drug testing models

Lee SJ, Lee HA

In vivo animal models are limited in their ability to mimic the extremely complex systems of the human body, and there is increasing disquiet about the ethics of animal research....
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Comparison of Nutrient Intake between Hypercholesterolemic and Normal groups based on the 6th Korea National Health and Nutrition Examination Survey

Lee HA, Kim HS

Objectives This study was conducted to compare the nutrient intake of normal healthy adults with those having hypercholesterolemia. Methods We analyzed data from the 6th Korea National Health and Nutrition Examination Survey (KNHANES...
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