Korean J Neurogastroenterol Motil.
2006 Dec;12(2):161-165.
Segmental Colonic Hypoganglionosis in an Adult Patient
- Affiliations
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- 1Department of Internal Medicine, Chonbuk National University College of Medicine, Jeonju, Korea. soo@chonbuk.ac.kr
- 2Department of General Surgery, Chonbuk National University College of Medicine, Jeonju, Korea.
- 3Department of Pathology, Chonbuk National University College of Medicine, Jeonju, Korea.
Abstract
- Colonic hypoganglionosis is one variant of the colonic ganglion cell disorders. It is characterized histologically by a small number of ganglion cells in the intestinal myenteric plexuses and it's characterized functionally by severely impaired gut motility. Most cases reported in the literature have occurred relatively late in childhood, and they usually involve mild constipation. In our case, the patient had a megacolon with severe constipation. He had had repeated admissions due to chronic constipation and abdominal distention. Conservative management failed to relieve those symptoms, and so subtotal colectomy was undergone. The patient recovered normal bowel habits in five months after his operation.
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