Soonchunhyang Med Sci.
2015 Jun;21(1):36-39. 10.0000/sms.2015.21.1.36.
A Case of Colonic Hypoganglionosis Complicated with Colonic Ulcers
- Affiliations
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- 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. drpsy@naver.com
- 2Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.
- 3Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
- KMID: 1797810
- DOI: http://doi.org/10.0000/sms.2015.21.1.36
Abstract
- Hypoganglionosis is a rare form of intestinal neuronal malformation, which is characterized by reduced number and size of ganglion cells of parasympathetic nerves in the intestinal wall. Pathophysiology is not well known, however intestinal ischemia, inflammation, autoimmune process or neurotoxin may play a role. Here, we report the case of a 56-year-old man with colonic pseudoobstruction and ulcerations in marked dilatedcolon above transitional zone who was later diagnosed with colonic hypoganglionosis.
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