Korean J Nephrol.  1997 Sep;16(3):607-611.

Exercise-induced Acute Renal Failure Associated with Nonsteoidal Anti-inflammatory Drugs: Report of 2 Cases

Affiliations
  • 1Department of Internal Medicine, Korea University, Seoul, Korea.
  • 2Department of Radiology, Korea University, Seoul, Korea.
  • 3Department of Internal Medicine, Dongbu Municipal Hospital, Seoul, Korea.

Abstract

Acute nonmyoglobinuric renal failure with severe loin pain and patchy renal vasoconstriction is a clinical syndrome that occurs following exercise in previously healthy young persons. Also nonsteroidal anti-inflammatory drugs predispose to acute renal failure in conditions associated with decreased renal blood flow. Probably exercise-induced renal ischemia and prostaglandin inhibition by NSAIDs may predispose to develop this syndrome. Here, we report two cases of acute renal failure with severe loin pain after strenuous exercise while taking NSAIDs with review of literature.

Keyword

Acute renal failure; Patchy renal vasoconstriction; Exercise

MeSH Terms

Acute Kidney Injury*
Anti-Inflammatory Agents, Non-Steroidal
Humans
Ischemia
Renal Circulation
Renal Insufficiency
Vasoconstriction
Anti-Inflammatory Agents, Non-Steroidal
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