Korean J Med.
2000 Jul;59(1):74-79.
A case of eosinophilic gastroenteritis with diffuse small bowel edema and ascites
- Affiliations
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- 1Department of Internal Medicine, Sung Kyun Kwan University College of Medicine, Kangbuk Samsung Hospital, Seoul, Korea. ligua@samsung.co.kr
- 2Department of Pathology, Sung Kyun Kwan University College of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.
- 3Department of Department of Internal Medicine, Pochon CHA university College of Medicine, Pochon, Korea.
Abstract
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Eosinophilic gastroenteritis is an uncommon disorder of stomach, small bowel and colon
characterized by peripheral blood eosinophilia, eosinophilic infiltration of the gut wall,
and variable clinical symptoms. This disease was first described by Kaijser in 1937,
and its cause was poorly understood. It may be related to allergy, which combines allergic
rhinitis, allergic asthma, atopic dermatitis, food allergy and elevated IgE. The clinical
symptoms and signs are variable according to the extents and depths of the eosinophilic
infiltration. Endoscopic findings may show normal, nodular, ulcerative, or hemorrhagic mucosal
changes, and biopsy findings reveal eosinophilic infiltration of mucosal and muscular layer.
We diagnosed and treated a case of diffuse serosal eosinophilic gastroenteritis associated with
ascites in a patient with allergic asthma who had severe abdominal pain, distention and watery
diarrhea, and she dramatically responded to corticosteroid therapy.