Korean J Infect Dis.
2002 Feb;34(1):64-68.
A Case Report of Postoperative Herpes Simplex Viral Pneumonia in a Patient with Tracheal Adenoid Cystic Carcinoma
- Affiliations
-
- 1Department of Pulmonology and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea. yhwa1805@madang.ajou.ac.kr
- 2Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
Abstract
- Herpes simplex virus (HSV) infection of the lower respiratory tract occurs rarely in neonate and immunocompromised host. The need for a timely and specific diagnosis of viral infections is becoming greater with development of antiviral chemotherapy. Herein, we report a case of herpes simplex virus pneumonia diagnosed by cytologic examination of the bronchoalveolar lavage (BAL) sample of respiratory epithelial cells in a tracheal adenoid cystic carcinoma patient. A 65-year-old woman presented with dyspnea and cough for one month. Bronchoscopy showed a mass arising from the posterior wall of upper trachea, and she underwent tracheal sleeve resection with cricotracheal anastomosis. The pathologic examination revealed adenoid cystic carcinoma. Corticosteroids were used for prevention of stenosis and swelling on the anastomosis site. On 28th postoperative day, pneumonia developed and it was aggravated despite of antibiotic therapy. The cytologic examination of the BAL fluid showed the eosinophilic nuclear inclusion along with the positive result of immunocytochemistry using monoclonal antibody to HSV. Despite of immediate therapy with acyclovir the pneumonia progressed to the acute respiratory distress syndrome and the patient eventual died.
MeSH Terms
-
Acyclovir
Adenoids*
Adrenal Cortex Hormones
Aged
Bronchoalveolar Lavage
Bronchoscopy
Carcinoma, Adenoid Cystic*
Constriction, Pathologic
Cough
Diagnosis
Drug Therapy
Dyspnea
Eosinophils
Epithelial Cells
Female
Herpes Simplex*
Humans
Immunocompromised Host
Immunohistochemistry
Infant, Newborn
Intranuclear Inclusion Bodies
Pneumonia
Pneumonia, Viral*
Respiratory Distress Syndrome, Adult
Respiratory System
Simplexvirus
Trachea
Acyclovir
Adrenal Cortex Hormones
