Korean J Dermatol.
2008 Apr;46(4):503-506.
A Case of Bullae and Eccrine Sweat Gland Necrosis in a Patient with Drug-Induced Coma
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- 1Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. miumiu@amc.seoul.kr
Abstract
- Coma-induced bullae and sweat gland necrosis is a rare clinicopathologic entity often associated with alcohol intake or drug abuse (barbiturate and benzodiazepine overdose). Local pressure and hypoxia are considered to be important causative factors. But, the exact pathogenesis remains unknown. Herein, we report a case with clinical and histologic findings characteristic of blisters and sweat gland necrosis occurring in a drug-induced comatose patient.
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