Korean J Biol Psychiatry.  2013 May;20(2):29-30.

Ketamine as a Rapid-Acting Antidepressant

Affiliations
  • 1Department of Neuropsychiatry, Hanyang University College of Medicine, Guri Hospital, Guri, Korea. daeyoh@kaist.ac.kr

Abstract

First-line therapy of depression is a pharmacological treatment. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. Recently, Ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. Here, I introduce ketamine as a rapid-acting antidepressant.

Keyword

Depression; NMDA; Ketamine; mTOR

MeSH Terms

Antidepressive Agents
Depression
Dopamine
Ketamine
N-Methylaspartate
Neurotransmitter Agents
Norepinephrine
Serotonin
Antidepressive Agents
Dopamine
Ketamine
N-Methylaspartate
Neurotransmitter Agents
Norepinephrine
Serotonin
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