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Easy sedation anesthesia guide for non-anesthetic medical personnel

Min TJ

Currently, sedation anesthesia is increasingly used in many medical fields, from gastroscopy to medical imaging. The demand for sedation anesthesia is expected to increase gradually with increasing number of day...
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Treatment of severe pain in a patient with complex regional pain syndrome undergoing dental treatment under general anesthesia: A case report

Rhee SH, Park SH, Ha SH, Ryoo SH, Karm MH, Kim HJ, Seo KS

Complex regional pain syndrome (CRPS) is rare, characterized by pain from diverse causes, and presents as extreme pain even with minor irritation. General anesthesia may be required for dental treatment...
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Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine

Schuetze S, Manig A, Ribes S, Nau R

Geriatric animal models are crucial for a better understanding and an improved therapy of age-related diseases. We observed a high mortality of aged mice after anesthesia with a standard dose...
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Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...
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Is Advancing Circadian Rhythm the Mechanism of Antidepressants?

Lee HJ

Antidepressants usually require 2–8 weeks after drug administration to obtain a clinical response. In contrast, three fast-acting antidepressant treatments (sleep deprivation, electroconvulsive therapy, and ketamine) significantly reduced depressive symptoms within...
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Factors affecting determination of the optimal ketamine dose for pediatric sedation

Min JY, Lee JR, Kim HI, Byon HJ

OBJECTIVE: Children are sedated before undergoing diagnostic imaging tests in emergency medicine or pediatric sedation anesthesia units. The aim of this study was to identify variables potentially affecting the dose...
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Low-dose intravenous ketamine versus intravenous ketorolac in pain control in patients with acute renal colic in an emergency setting: a double-blind randomized clinical trial

Sotoodehnia M, Farmahini-Farahani M, Safaie A, Rasooli F, Baratloo A

BACKGROUND: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). METHODS: This...
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A comparison of clinical performance between i-gel and endotracheal tube in pediatric laparoscopic surgeries

Hong JI, Lee TY, Park SY, Choi SR, Lee SC, Chung CJ, Kim JH

BACKGROUND: The current evidence on the safe use of supraglottic airway for pediatric laparoscopic surgeries is limited. Although i-gel has been successfully used in adult laparoscopic surgeries, to our knowledge,...
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Abnormalities in Inflammatory Cytokines Confer Susceptible to Chronic Neuropathic Pain-related Anhedonia in a Rat Model of Spared Nerve Injury

Fang X, Zhan G, Zhang J, Xu H, Zhu B, Hu Y, Yang C, Luo A

OBJECTIVE: Patients with chronic neuropathic pain (CNP) have a higher incidence to develop depression. However, its pathogenesis has not yet been fully elucidated. Here we aimed to investigate the role...
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Chronic administration of ketamine ameliorates the anxiety- and aggressive-like behavior in adolescent mice induced by neonatal maternal separation

Shin SY, Baek NJ, Han SH, Min SS

Ketamine has long been used as an anesthetic agent. However, ketamine use is associated with numerous side effects, including flashbacks, amnesia, delirium, and aggressive or violent behavior. Ketamine has also...
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Designing the ideal perioperative pain management plan starts with multimodal analgesia

Schwenk ES, Mariano ER

Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while...
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Ketamine with Propofol for Endoscopic Procedures

Bhalotra A

No abstract available.
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Chronic postsurgical pain: current evidence for prevention and management

Thapa P, Euasobhon

Chronic postsurgical pain (CPSP) is an unwanted adverse event in any operation. It leads to functional limitations and psychological trauma for patients, and leaves the operative team with feelings of...
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Rapid-Acting Antidepressant Effect of Ketamine and Its Clinical Application

Kim YK, Shin C

Although the biological causes of depression have been well established, the current use of antidepressants are still mostly based on the monoamine hypothesis of depression. However, monoamine antidepressants delay treatment...
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A Comparison of Sedation with Ketamine-Midazolam versus Ketamine-Propofol for the Lumbar Puncture in Children

Ko YR, Jeon W, Kwak JR, Lee JS

PURPOSE: This study was conducted to compare the safety and effectiveness of intravenous ketamine-midazolam (KM) and ketamine-propofol (KP) combination for the lumbar puncture (LP) procedure in children. METHODS: This was a...
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Comparison of propofol alone and in combination with ketamine or fentanyl for sedation in endoscopic ultrasonography

Singh SA, Prakash K, Sharma S, Dhakate G, Bhatia V

BACKGROUND: We evaluated whether the addition of a small dose of ketamine or fentanyl would lead to a reduction in the total dose of propofol consumed without compromising the safety...
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The Therapeutic Effect of Human Embryonic Stem Cell-Derived Multipotent Mesenchymal Stem Cells on Chemical-Induced Cystitis in Rats

Lee SW, Ryu CM, Shin JH, Choi D, Kim A, Yu HY, Han JY, Lee HY, Lim J, Kim YH, Heo J, Lee S, Ju H, Kim S, Hong KS, Han JY, Song M, Chung HM, Kim JK, Shin DM, Choo MS

PURPOSE: To evaluate the therapeutic effect of human embryonic stem cell (hESC)-derived multipotent mesenchymal stem cells (M-MSCs) on ketamine-induced cystitis (KC) in rats. METHODS: To induce KC, 10-week-old female rats were...
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Application of Monitored Anesthesia Care Using Dexmedetomidine to Common Oral and Maxillofacial Trauma Cases

Lee DW, Shin MC, Hong SO

Oral and maxillofacial surgery (OMFS) trauma cases are commonly treated under general anesthesia. The purpose of this case report is to introduce an alternative method of anesthesia in patients who...
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Considerations for physicians using ketamine for sedation of children in emergency departments

Kim WS, Ku JY, Choi H, Choi HJ, Kim HJ, Lee B

OBJECTIVE: Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine....
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Perioperative Hypertension Management during Facelift under Local Anesthesia with Intravenous Hypnotics

Chung KH, Cho MS, Jin H

Perioperative hypertension is a phenomenon in which a surgical patient's blood pressure temporarily increases throughout the preoperative and postoperative periods and remains high until the patient's condition stabilizes. This phenomenon...
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