Korean J Anesthesiol.  1978 Sep;11(3):233-238.

Ketamine in Obstetric Anesthesia

• Park MJ
• Jeoung BY
• Cho YL

Abstract

The pharmacologic actions of ketamine in human volunteers were reported by Domino et al in 1965 and it was used in 130 patients by Corssen Domino in 1966. Chodoff and Stella were the first to investigate ketamines suitabilityas an in anesthetic in childbirth. Since then several authors reported that ketamine has several advantages over conventional anesthetics in obstetric anesthesia. Ketamine was used as the sole anesthetic agent for forceps delivery in 50 women who were selected randomly. Ketamine was administered intravenously just before delivery in doses of 30 to 60 mg and after delivery dosage was not limited, The following results were observed: 1) During delivery, a rapid and intense analgesic effect was sufficiently maintained with a small dose of ketamine. 2) With the use of ketarnine it is possible to shorten the second stage of labor with a short induction-delivery-interval because of the advantages of forceps delivery. 3) Ketamine could be used without intubation during with a short fasting time because protective laryngeal quate airway could be maintained. 4) Ketamine did not appear to induce an increase of Very. delivery even in patients and pharyngeal reflexes and an ade uterine bleeding during or after deli 5) The use of ketamine during delivery appeared to have almost no affect on the Apgar score. 6) The use of ketamine was accompanied by mild complications but they were not significant.

MeSH Terms

Anesthesia, Obstetrical*
Anesthetics
Apgar Score
Fasting
Female
Gagging
Healthy Volunteers
Humans
Intubation
Ketamine*
Parturition
Pharmacologic Actions
Surgical Instruments
Uterine Hemorrhage
Anesthetics
Ketamine
Pharmacologic Actions