Korean J Asthma Allergy Clin Immunol.  2011 Sep;31(3):219-222.

A Case of Levodropropizine-induced Anaphylaxis

Abstract

BACKGROUND
Anaphylaxis is one of the severe adverse drug reactions. Levodropropizine acts as a peripheral antitussive with no action in the central nervous system and thus does not cause side effects, such as constipation and respiratory depression, which can be produced by opioid antitussives, including as codein and its derivatives. Levodropropizine is known to be safe and is commonly used as an antitussive drug. CASE HISTORY: There has been only 1 report of adult case of anaphylaxis caused by levodroprozine. We experienced the case of a 4 year-old boy who developed recurrent generalized urticaria and confusion after ingestion of levodropropizine.
RESULTS
The case was confirmed by skin prick test and oral provocation test.
CONCLUSION
We report one case of anaphylaxis of levodropropizine. Thus levodropropizine should be considered le the causes in patients with drug-induced anaplylaxis.

MeSH Terms

Adult
Anaphylaxis
Antitussive Agents
Central Nervous System
Constipation
Drug Toxicity
Eating
Humans
Propylene Glycols
Respiratory Insufficiency
Skin
Skin Tests
Urticaria
Antitussive Agents
Propylene Glycols