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Challenges and Pitfalls of Stroke Therapeutics Research

Jung KH

  • KMID: 2288739
  • Korean J Stroke.
  • 2011 Apr;13(1):11-15.
Ischemia-reperfusion injury is complicated with multiple injury pathways. If a particular agent is used to restore blood flow and prevent cell death, many damaged neurons may come back to life....
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A Case of Allergic Contact Dermatitis to Duoderm Extrathin(R) Dressing

Seo JK, Lee HJ, Hong SK, Lee D, Choi HC, Sung HS, Hwang SW

  • KMID: 2301691
  • Korean J Dermatol.
  • 2009 Feb;47(2):220-222.
Even though hydrocolloid dressings have been widely used for the past 15 years in the treatment of various types of wounds; allergic contact dermatitis to these dressings have been rarely...
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A Case of Immunoglobulin E Mediated Anaphylaxis to Levodropropizine

Park KH, Yun IS, Choi SY, Lee JH, Hong CS, Park JW

We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and...
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A Case of Levodropropizine-induced Anaphylaxis

  • KMID: 2299505
  • Korean J Asthma Allergy Clin Immunol.
  • 2011 Sep;31(3):219-222.
BACKGROUND: Anaphylaxis is one of the severe adverse drug reactions. Levodropropizine acts as a peripheral antitussive with no action in the central nervous system and thus does not cause side...
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Quantitative Exposure Assessment of Various Chemical Substances in a Wafer Fabrication Industry Facility

Park H, Jang JK, Shin JA

  • KMID: 2316999
  • Saf Health Work.
  • 2011 Mar;2(1):39-51.
OBJECTIVES: This study was designed to evaluate exposure levels of various chemicals used in wafer fabrication product lines in the semiconductor industry where work-related leukemia has occurred. METHODS: The research focused...
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Interferon beta-1b Treatment in a Korean Girl with Multiple Sclerosis

Kim HJ, Kim HD, Lee JS, Kang HC

  • KMID: 2329623
  • J Korean Child Neurol Soc.
  • 2013 Mar;21(1):28-32.
Here we report a case of pediatric multiple sclerosis treated with interferon beta-1b. Interferon beta is widely used in adult patients with multiple sclerosis (MS). However, its effects and safety...
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Reformation of post-graduate medical education system in Korea

Wang KC

Revision of the post-graduate medical education (PGME) system, which has been almost fixed since the introduction of the intern-resident training system in Korea more than 50 years ago, is particularly...
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New Antiepileptic Drugs in Childhood Epilepsy

Chung S

Many new antiepileptic drugs (AEDs) have been developed in the last two decades, contributing to the optimal treatment for childhood epilepsy. The goal of the treatment is to achieve seizure-free...
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New antiepileptic drugs. II. Clinical use

Lee BI

No abstract available.
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The Efficacy of Inhaled Corticosteroid on Chronic Idiopathic Cough

Han B, Jang SH, Kim YJ, Park S, Hwang YI, Kim DG, Kim CH, Hyun IG, Jung KS

  • KMID: 2319279
  • Tuberc Respir Dis.
  • 2009 Nov;67(5):422-429.
BACKGROUND: The discomfort caused by chronic cough, that is persistent for more than 3 weeks, causes a number of patients to seek medical attention. However, the underlying disorder often remains...
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FTY720: Mechanism of Action and Potential Benefit in Organ Transplantation

Brinkmann

FTY720 is a novel immunomodulator that has proven effective in animal models of transplantation and autoimmunity, has achieved promising results in Phase I and Phase II studies of renal transplantation...
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Sphingosine mediates FTY720-induced apoptosis in LLC-PK1 cells

Lee WJ, Yoo HS, Suh PG, Lim JS, Oh S, Lee YM

  • KMID: 1123763
  • Exp Mol Med.
  • 2004 Oct;36(5):420-427.
FTY720, a synthetic sphingoid base analog, was examined as a new sphingosine kinase inhibitor, which converts endogenous sphingosine into its phosphate form. With 20 micrometer of FTY720, sphingosine accumulated in...
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Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model

Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY

  • KMID: 1506224
  • Exp Mol Med.
  • 2012 Oct;44(10):603-614.
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P),...
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