Korean J Urol.  2004 Oct;45(10):1062-1065.

Complete Remission of Renal Cell Carcinoma with Metastases to Lung and Bone Following Initial Interferon-alpha Immunotherapy and Adjuvant Nephrectomy

Affiliations
  • 1Department of Urology, Seoul Veterans Hospital, Seoul, Korea. hb0282@hanmail.net

Abstract

Patients with metastatic renal cell carcinomas have a median survival of less than 1 year and a 0-20% 5-year survial. The immunotherapy agent interferon-alpha has consistently produced objective responses rarely exceeding 20% of treated patients. Moreover, in patients with metastases to brain, liver or bone, the prognosis is extremely poor. A 66-year-old man, with a right renal cell carcinoma, with metastases to lung and bone who had entered a remarkable complete radiological remission of the metastases to lung and bone by 82 months following interferon-alpha immunotherapy, underwent a nephrectomy. The patient has remained recurrence free for 16 months after the nephrectomy.

Keyword

Renal cell carcinoma; Metastases; Interferon-alpha; Nephrectomy

MeSH Terms

Aged
Brain
Carcinoma, Renal Cell*
Humans
Immunotherapy*
Interferon-alpha*
Liver
Lung*
Neoplasm Metastasis*
Nephrectomy*
Prognosis
Recurrence
Interferon-alpha
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