- Establishment of patient-derived three-dimensional organoid culture in renal cell carcinoma
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Na JC, Kim JH, Kim SY, Gu YR, Jun DY, Lee HH, Yoon YE, Choi KH, Hong SJ, Han WK
- KMID: 2471078
- Investig Clin Urol.
- 2020 Mar;61(2):216-223.
- doi: 10.4111/icu.2020.61.2.216
PURPOSE: Renal cell carcinoma is a heterogeneous kidney cancer, and over 403,000 cases were reported worldwide in 2018. Current methods for studying renal cell carcinoma are limited to two-dimensional (2D)... -
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- Survival prognoses of Heng intermediate-risk patients with metastatic renal cell carcinoma treated with immunotherapy or targeted therapy: A real-world, single-center retrospective study
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Kim SH, Lee DE, Joung JY, Seo HK, Lee KH, Chung J
- KMID: 2471070
- Investig Clin Urol.
- 2020 Mar;61(2):146-157.
- doi: 10.4111/icu.2020.61.2.146
PURPOSE: This study aimed to compare progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS) in Heng intermediate-risk patients with metastatic renal cell carcinoma (mRCC) treated with first-line immunotherapy... -
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- Impact of perioperative blood transfusion on oncologic outcomes in patients with nonmetastatic renal cell carcinoma treated with curative nephrectomy: A retrospective analysis of a large, single-institutional cohort
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Seon DY, Kwak C, Kim HH, Ku JH, Kim HS
- KMID: 2471069
- Investig Clin Urol.
- 2020 Mar;61(2):136-145.
- doi: 10.4111/icu.2020.61.2.136
PURPOSE: To evaluate the impact of perioperative blood transfusion (PBT) on oncologic outcomes after surgery in patients with nonmetastatic renal cell carcinoma (RCC). MATERIALS AND METHODS: This retrospective review included 2,329... -
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- Characteristics of Renal Cell Carcinoma Harboring TPM3-ALK Fusion
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Woo CG, Yun SJ, Son SM, Lim YH, Lee OJ
- KMID: 2470924
- Yonsei Med J.
- 2020 Mar;61(3):262-266.
- doi: 10.3349/ymj.2020.61.3.262
The World Health Organization 2016 edition assigned anaplastic lymphoma kinase (ALK) rearrangement-associated renal cell carcinoma (ALK-RCC) as an emerging renal tumor entity. Identifying ALK-RCC is important because ALK inhibitors have... -
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- Acute Acalculous Cholecystitis Associated with Sunitinib Treatment for Renal Cell Carcinoma
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Choi SW, Lee JM, Kim DG, Noh MH
- KMID: 2471150
- Korean J Gastroenterol.
- 2020 Feb;75(2):103-107.
- doi: 10.4166/kjg.2020.75.2.103
A 64-year-old man was treated with sunitinib as a first-line therapy for metastatic renal cell carcinoma. He was given oral sunitinib in cycles of 50 mg once daily for 2... -
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- Involvement of the TNF-α Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma
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Hwang HS, Park YY, Shin SJ, Go H, Park JM, Yoon SY, Lee JL, Cho YM
- KMID: 2469348
- J Korean Med Sci.
- 2020 Feb;35(5):e31.
- doi: 10.3346/jkms.2020.35.e31
BACKGROUND: Mechanism and predictive biomarkers for tyrosine kinase inhibitor (TKI) resistance of advanced clear cell renal cell carcinoma (ccRCC) have not been fully evaluated. METHODS: We performed gene expression profiling on... -
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- Prognostic Significance of Systemic Inflammatory Response in Patients with Synchronous and Metachronous Metastatic Renal Cell Carcinoma Receiving First-Line Tyrosine Kinase Inhibitors
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Choi J, Kim TJ, Sung HH, Jeon HG, Jeong BC, Jeon SS, Lee HM, Choi HY, Kang M, Seo SI
- KMID: 2470400
- Korean J Urol Oncol.
- 2019 Dec;17(3):150-159.
- doi: 10.22465/kjuo.2019.17.3.150
PURPOSE: To determine whether systemic inflammatory response (SIR), particularly platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR), has different prognostic role between patients with metastatic renal cell carcinoma (mRCC) receiving first-line... -
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- Clinical features and outcomes in kidney transplant recipients with renal cell carcinoma: a single-center study
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Park KH, Yoon JA, Kim HS, Kim H, Park SK, Kim YH, Hong B, You D, Jeong IG, Baek CH
- KMID: 2469382
- Kidney Res Clin Pract.
- 2019 Dec;38(4):517-524.
- doi: 10.23876/j.krcp.19.078
BACKGROUND: Previous studies have recommended a 2- to 5-year waiting time prior to kidney transplantation (KT) in patients with end-stage renal disease (ESRD) and symptomatic renal cell carcinoma (RCC) and... -
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- Cutaneous metastatic renal cell carcinoma to the scalp
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Yang HJ, Kang SY
- KMID: 2468779
- Arch Craniofac Surg.
- 2019 Dec;20(6):392-396.
- doi: 10.7181/acfs.2019.00206
Renal cell carcinoma (RCC) represents 2% to 3% of human cancers and is aggressive, with metastatic capability. The frequent metastatic sites are lung, bone, and liver. Reports of RCC metastatic... -
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- Prolyl hydroxylase-3 is a novel renal cell carcinoma biomarker
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Kim KH, Lee HH, Yoon YE, Na JC, Kim KS, Han WK
- KMID: 2461053
- Investig Clin Urol.
- 2019 Nov;60(6):425-431.
- doi: 10.4111/icu.2019.60.6.425
PURPOSE: The aim of this study was to determine the suitability of serum prolyl hydroxylase-3 (PHD3) as a diagnostic or monitoring biomarker of renal cell carcinoma (RCC). MATERIALS AND METHODS: Between... -
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- Neutrophil-to-Lymphocyte Ratio Predicts Pathological Renal Sinus Fat Invasion in Renal Cell Carcinomas of ≤7 cm with Presumed Renal Sinus Fat Invasion
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Kim J, Park JS, Heo JE, Elghiaty A, Jang WS, Rha KH, Choi YD, Ham WS
- KMID: 2460218
- Yonsei Med J.
- 2019 Nov;60(11):1021-1027.
- doi: 10.3349/ymj.2019.60.11.1021
PURPOSE: Computed tomography (CT) is the most useful diagnostic modality for staging renal cell carcinoma (RCC). However, CT is limited in its ability to predict renal sinus fat invasion (SFI).... -
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- A Two-DNA Methylation Signature to Improve Prognosis Prediction of Clear Cell Renal Cell Carcinoma
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Shi S, Ye S, Wu X, Xu M, Zhuo R, Liao Q, Xi Y
- KMID: 2460217
- Yonsei Med J.
- 2019 Nov;60(11):1013-1020.
- doi: 10.3349/ymj.2019.60.11.1013
PURPOSE: Effective biomarkers and models are needed to improve the prognostic prospects of clear cell renal cell carcinoma (ccRCC). The purpose of this work was to identify DNA methylation biomarkers... -
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- Bevacizumab Plus Erlotinib Combination Therapy for Advanced Hereditary Leiomyomatosis and Renal Cell Carcinoma-Associated Renal Cell Carcinoma: A Multicenter Retrospective Analysis in Korean Patients
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Choi Y, Keam B, Kim M, Yoon S, Kim D, Choi JG, Seo JY, Park I, Lee JL
- KMID: 2460603
- Cancer Res Treat.
- 2019 Oct;51(4):1549-1556.
- doi: 10.4143/crt.2019.086
PURPOSE: Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a rare genetic syndrome resulting from germline mutations in fumarate hydratase. The combination of bevacizumab plus erlotinib showed promising interim results... -
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- Early Experiences with Nivolumab in Patients with Metastatic Renal Cell Carcinoma and Failed Target Therapy
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Lee JH, Kang M, Chung JH, Sung HH, Jeon HG, Jeong BC, Jeon SS, Lee HM, Park SH, Kim B, Kwon GY, Seo SI
- KMID: 2457593
- Korean J Urol Oncol.
- 2019 Aug;17(2):96-102.
- doi: 10.22465/kjuo.2019.17.2.96
PURPOSE: The efficacy of nivolumab in metastatic renal cell carcinoma (mRCC) has been proven. However, the nivolumab experience in Korean patients with mRCC is still poorly reported. We report initial... -
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- The pancreas as a target of metastasis from renal cell carcinoma: Results of surgical treatment in a single institution
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Glinka J, Sanchez Claria R, Ardiles V, de Santibañes E, Pekolj J, de Santibañes M, Mazza O
- KMID: 2456021
- Ann Hepatobiliary Pancreat Surg.
- 2019 Aug;23(3):240-244.
- doi: 10.14701/ahbps.2019.23.3.240
BACKGROUNDS/AIMS: Metastasis in the pancreatic gland is infrequent, representing between 2–5% of the tumors that affect this organ. However, secondary lesions of clear cell renal carcinoma (CCRC) can occur mainly... -
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- Letter to the editor: Prognostic significance of preoperative and follow-up neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with non-metastatic clear cell renal cell carcinoma
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Joob B, Wiwaniitkit V
- KMID: 2450552
- Investig Clin Urol.
- 2019 Jul;60(4):331-332.
- doi: 10.4111/icu.2019.60.4.331
No abstract available. -
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- Methylation Signature for Prediction of Progression Free Survival in Surgically Treated Clear Cell Renal Cell Carcinoma
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Kang HW, Park H, Seo SP, Byun YJ, Piao XM, Kim SM, Kim WT, Yun SJ, Jang W, Shon HS, Ryu KH, Lee SC, Kim WJ, Kim YJ
- KMID: 2445802
- J Korean Med Sci.
- 2019 May;34(19):e144.
- doi: 10.3346/jkms.2019.34.e144
BACKGROUND: Little is known about epigenetic silencing of genes by promoter hypermethylation in renal cell carcinoma (RCC). The aim of this study was to identify prognostic methylation markers in surgically... -
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- SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change
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Kim SH, Park WS, Chung J
- KMID: 2444268
- Investig Clin Urol.
- 2019 May;60(3):148-155.
- doi: 10.4111/icu.2019.60.3.148
PURPOSE: Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) and clear cell renal cell carcinoma with cystic change (MCRCC) have different prognoses despite similar histologic characteristics. The aim of... -
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- Application of the International Metastatic Renal Cell Carcinoma Database Consortium and Memorial Sloan Kettering Cancer Center Risk Models in Patients with Metastatic Non-Clear Cell Renal Cell Carcinoma: A Multi-Institutional Retrospective Study Using the Korean Metastatic Renal Cell Carcinoma Registry
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Kim JK, Kim SH, Song MK, Joo J, Seo SI, Kwak C, Jeong CW, Song C, Hwang EC, Seo IY, Lee H, Hong SH, Park JY, Chung J, Korean Renal Cell Carcinoma Study Group
- KMID: 2464421
- Cancer Res Treat.
- 2019 Apr;51(2):758-768.
- doi: 10.4143/crt.2018.421
PURPOSE: The International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) and the Memorial Sloan Kettering Cancer Center (MSKCC) risk models were developed predominantly with clear cell renal cell carcinoma (RCC).... -
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- Potential Oncogenic Role of the Papillary Renal Cell Carcinoma Gene in Non-Small Cell Lung Cancers
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Jang SH, Jiang Y, Shin S, Jung SH, Jung CK, Chung YJ
- KMID: 2450187
- Yonsei Med J.
- 2019 Apr;60(4):326-335.
- doi: 10.3349/ymj.2019.60.4.326
PURPOSE: Papillary renal cell carcinoma (PRCC) gene, which located in 1q23.1, is recurrently amplified in non-small cell lung cancer (NSCLC). However, it is unknown whether PRCC is overexpressed in primary... -
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