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A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years

Kwak M, Yeh HR, Yum MS, Kim HJ, You SJ, Ko TS

Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of...
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Repeated Panniculitis Induced by Pegylated Interferon Alpha 2a in a Patient with Chronic Hepatitis C

Song JS, Sohn JH, Jeong JY, Min JH, Choi WS, Kim OZ, Pyo JY

Pegylated interferon alpha (PEG-IFN-α) is widely used to treat chronic hepatitis C in combination with ribavirin. Many adverse effects of PEG-IFN-α, such as hematologic, psychologic, dermatologic, immunologic, and other abnormalities,...
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Cutaneous Ulceration after Injection of Interferon Alpha in a Melanoma Patient

Seo J, Lee YI, Lee JW, Chung KY

  • KMID: 2162230
  • Korean J Dermatol.
  • 2016 Mar;54(3):220-221.
No abstract available.
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Resolution of Type 2 Diabetes Mellitus Following Interferon-alpha Therapy for Chronic Hepatitis C

Park HS, Kim YJ, Moon SY, Woo JY, Choi JK, Kim KU, Park JR, Son HY, Kim DM

Hepatitis C virus (HCV) mainly affects the liver, but several tissues outside the liver have also been reported to be involved. It has been hypothesized that diabetes could be one...
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Interferon-Alpha Induced Severe Hypothyroidism Followed by Graves' Disease in a Patient Infected with Hepatitis C Virus

Kim KJ, Lee KW, Choi JH, An JH

Interferon-alpha (IFN-alpha) is an important therapeutic agent for hepatitis C virus (HCV) infection, but has various side effects including thyroiditis. We report a case of interferon-induced non-autoimmune hypothyroidism followed by...
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A Case of Kasabach-Merritt Syndrome Successfully Treated with Interferon-alpha 2b and Propranolol

Lee JW, Jung HL, Shim JW, Kim DS, Shim JY, Park MS, Park HJ

Kasabach-Merritt syndrome (KMS) is a rare, life-threatening disease characterized by rapidly enlarging hemangioma and consumptive coagulopathy. We report a case of KMS in a 28-day-old female neonate with a huge...
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Three Cases of Classic Kaposi Sarcoma Treated with Pegylated Interferon Alpha 2a Intralesional Injection

Jeong YI, Huh JW, Kim G, Kim EJ, Park HJ, Jue MS

  • KMID: 2089038
  • Korean J Dermatol.
  • 2014 Sep;52(9):646-650.
Kaposi sarcoma (KS) is a multifocal proliferative vascular tumor often caused by human herpes virus 8. Among the four subtypes of KS, classic KS (CKS) is usually chronic, persisting over...
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Azidothymidine and recombinant human interferon-alpha therapy in a cat with feline immunodeficiency virus

Jang HJ, Ho YK, Kang MH, Kim SG, Park WJ, Choi IS, Kim DY, Park HM

  • KMID: 1709212
  • J Biomed Res.
  • 2014 Jun;15(2):96-99.
A 7-year-old, spayed female, domestic short hair cat showed signs of a 2-week history of chronic anorexia, depression, and severe weight loss. Upon physical examination, pyrexia, mild gingivitis, and pale...
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Interferon-alpha inhibits airway eosinophila and hyperresponsiveness in an animal asthma model

Kikkawa Y, Sugiyama K, Obara K, Hirata H, Fukushima , Toda M, Fukuda T

BACKGROUND: Asthma is characterized by a chronic inflammatory process involving high numbers of inflammatory cells and mediators which have multiple inflammatory effects on the airway. Interferon (IFN)-alpha, which is used...
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A comparative study on the efficacy of different dosage of alpha-interferon treatment in patients with chronic hepatitis B

Kim TH, Kim CW, Cho KJ, Han SW, Cheong DY, Kim JI, Choi KY

  • KMID: 2305896
  • Korean J Med.
  • 2007 Nov;73(5):464-473.
BACKGROUND: Infection with hepatitis B virus has been a major health problem. Chronic viral hepatitis B is the principal cause of chronic liver disease, cirrhosis, and hepatoma. A number of...
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Efficacy and Side Effects of Interferon Alpha Treatment in Kidney Transplant Recipients with Chronic Hepatitis C

Kim YK, Yoon HE, Kim SH, Choi BS, Bae SH, Choi JY, Yoon SK, Yang CW, Kim YS, Kim SY, Bang BK

  • KMID: 2253713
  • Korean J Nephrol.
  • 2007 Nov;26(6):725-731.
PURPOSE: Chronic hepatitis C is a common cause of liver disease in kidney transplant (KT) recipients and lessens the chances of patients and graft survival. We evaluated the efficacy and...
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Exacerbation of Sarcoidosis Following Interferon-alpha Therapy for Chronic Active Hepatitis C

Chang HJ, Choi EH, Kim IJ, Sim YS, Lee JH, Kim TH, Moon JW, Chun EM, Kim YK, Sung SH, Chang JH

Interferon alpha is an immunomodulator that is used as an antiviral agent to treat chronic active viral hepatitis C. However, interferon can induce or exacerbate sarcoidosis. We report a case...
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Mechanisms of Granulosa Cell Transition from Proliferation to Differentiation During the Ovulatory Process in Rodents: Role of Interferon-alpha System

Chun SY, Jeon MJ, Seo YM, Kim TS

  • KMID: 1830746
  • Korean J Fertil Steril.
  • 2006 Jun;33(2):75-83.
No abstract available.
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Short-Term High Expression of Interferon-Alpha Modulates Progression of Type 1 Diabetes in NOD Mice

Park MK, Seo SY, Hong SH, Kim HJ, Park EJ, Kim DK, Lee HJ

  • KMID: 1512940
  • Korean J Physiol Pharmacol.
  • 2006 Feb;10(1):39-44.
Type I diabetes (T1D) is an organ-specific autoimmune disease caused by the T cell-mediated destruction of the insulin-producing beta cells in the pancreatic islets. The onset of T1D is the...
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Comparative Genomics Study of Interferon-alpha Receptor-1 in Humans and Chimpanzees

Kim IC, Chi SW, Kim DW, Choi SH, Chae SH, Park HS

  • KMID: 2284673
  • Genomics Inform.
  • 2005 Dec;3(4):142-148.
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human...
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Long-term follow-up of alpha-interferon treatment in patients with HBeAg-positive chronic hepatitis B

Choi DR, Jang MK, Moon HK, Kim SM, Lee JH, Lee JY, Kim KH, Park JY, Lee JH, Kim HY, Yoo JY

  • KMID: 2081130
  • Korean J Med.
  • 2005 Aug;69(2):150-156.
BACKGROUND: Data on the long-term effects of interferon alpha (IFN) treatment on disease progression and mortality in patients with chronic hepatitis B (CHB) are limited. To evaluate factors that influence...
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Reversal of Marrow Fibrosis Following Imatinib Mesylate Therapy in a Patient with Chronic Myelogenous Leukemia Who Was Refractory to Interferon-alpha

Kim YS, Kim TH, Kim WC, Jeon YJ, Kil UH, Lee HK, Kim YS, Rho SY, Cho SG

No abstract available.
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Comparison of Therapeutic Efficacy between Lamivudine and Alpha-Interferon in Korean Children with Chronic Hepatitis B at Two Years after the Initiation of Treatment

Choe BH, Jang YC, Jang CH, Oh KW, Lee JH, Ko CW

  • KMID: 2279602
  • Korean J Pediatr.
  • 2005 Jan;48(1):55-62.
PURPOSE: We compared the therapeutic efficacy of lamivudine and alpha-interferon in children with chronic hepatitis B two years after the initiation of treatment, so that we could verify the safety...
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Complete Remission of Renal Cell Carcinoma with Metastases to Lung and Bone Following Initial Interferon-alpha Immunotherapy and Adjuvant Nephrectomy

Lee KY, Shin JH, Choi WJ, Kim YB, Lee JK, Jung TY, Shim HB

  • KMID: 2293680
  • Korean J Urol.
  • 2004 Oct;45(10):1062-1065.
Patients with metastatic renal cell carcinomas have a median survival of less than 1 year and a 0-20% 5-year survial. The immunotherapy agent interferon-alpha has consistently produced objective responses rarely...
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Interferon-alpha in the Treatment of Behcet's Disease

Ko HG, Han JW, Kim MH, Lee WG

  • KMID: 2125908
  • J Korean Ophthalmol Soc.
  • 2004 Oct;45(10):1674-1680.
PURPOSE: To determine the therapeutic efficacy of interferon-alpha on patients with Behcet's disease who have been resistant to conventional therapies. METHODS: We treated 22 eyes of 13 patients with interferon-alpha...
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