J Asthma Allergy Clin Immunol.  1999 Oct;19(5):724-729.

Food ( wheat flour ) dependent exerclse - induced anaphylaxis in asthmatics : related with the amont of wheat flour and exercise

• Kim MK
• Lee KS
• Kim MS

Abstract

A 25-year-old male with asthma suffered from generalized urticaria, angioedema and syncope associated with exercise after ingestion of food made with wheat flour. Skin prick test with bread showed strong positive reaction(++++), but with wheat flour, a weak positive(+). Challenge test with wheat flour, and food made with wheat flour, without or with exercise, were done several times. Exercise such as 25 min of running on treadmill following 30 min after 50 grams of bread or 50 grams of hot pepper-stuffed rice cake only showed positive reaction such as generalized urticaria, angioedema and hypotension, but not with 15 grams of bread or 15 grams of hot pepper-stuffed rice cake. Ingestion of bread in such high amounts as 15 grams alone did not trigger reaction, not even with is min of exercise. This is the first clear case of food dependent exercise induced anaphylaxis (FDEIA) in which the allergic reaction depended on both the amount of food ingested and the amount of exercise was clarified.

Keyword

FDEIA; dependent with the amount of food and exercise; asthmatics

MeSH Terms

Adult
Anaphylaxis*
Angioedema
Asthma
Bread
Eating
Flour*
Humans
Hypersensitivity
Hypotension
Male
Running
Skin
Syncope
Triticum*
Urticaria