Infect Chemother.  2009 Dec;41(6):362-365. 10.3947/ic.2009.41.6.362.

A Case of Lupus-like Glomerulonephritis in an HIV-infected Patient

• Yoon JH
• Chun SH
• Shin JY
• Lim BJ
• Kim YS
• Na KR
• Suh KS
• Lee KW
• Shin YT

• KMID: 2285043
• DOI: http://doi.org/10.3947/ic.2009.41.6.362

Abstract

Many types of glomerulonephritis are associated with human immunodeficiency virus (HIV) infection. We present a case of a 50-year-old Korean man with an HIV infection, who developed nephrotic syndrome and progressive renal failure. Renal biopsy showed lupus-like glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. After the administration of antiretroviral agents and steroids, there was reduction in the amount of proteinuria and improvement in renal function.

Keyword

Human immunodeficiency virus; Glomerulonephritis; HIV-associated Nephropathy

MeSH Terms

AIDS-Associated Nephropathy
Anti-Retroviral Agents
Biopsy
Glomerulonephritis
HIV
HIV Infections
Humans
Lupus Erythematosus, Systemic
Middle Aged
Nephrotic Syndrome
Proteinuria
Renal Insufficiency
Steroids
Anti-Retroviral Agents
Steroids

Figure

• 

  Figure 1 Pathologic findings of lupus-like glomerulonephritis with HIV infection. A) Diffuse endocapillary proliferation and crescent formation (arrow) are shown (sliver stain, LM, ×400). B) Grandular Ig G deposition is shown along the capillary wall (IFM, ×300). C) Grandular Ig A deposition is shown along the capillary wall (IFM, ×300. D) Tubuloreticular body of glomerulus(arrow) is shown in endothelial cell cytoplasm (EM, ×15,000).

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