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The Usefulness of Symptom-based Subtypes of Functional Dyspepsia for Predicting Underlying Pathophysiologic Mechanisms and Choosing Appropriate Therapeutic Agents

Lee KJ

  • KMID: 2517526
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):326-336.
  • doi: 10.5056/jnm21042
Functional dyspepsia (FD) is considered to be a heterogeneous disorder with different pathophysiological mechanisms or pathogenetic factors. In addition to traditional mechanisms, novel concepts regarding pathophysiologic mechanisms of FD have...
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Inhibitory effect of mangosteen peel and propolis ethanol extracts on alveolar bone loss against increased treatment amount of Porphyromonas gingivalis lipopolysaccharide in rat

Lee KH, Yoo SY, Kook JK, Sung SJ, Lee KW, Lim YK, Lee DS, Yu SJ

In previous studies, we introduced that mangosteen extract complex (MEC; ethanol extracts of Garcinia mangostana L. peel and propolis) had inhibitory effects on inflammation and alveolar bone loss in silk-ligature...
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Cell Type-specific Knockout with Gli1-mediated Cre Recombination in the Developing Cerebellum

Choi JM, Acharya R, Marasini S, Narayan B, Lee KW, Hwang WS, Chang DY, Kim SS, Kim HS

  • KMID: 2517473
  • Exp Neurobiol.
  • 2021 Jun;30(3):203-212.
  • doi: 10.5607/en21017
The inducible Cre-loxP system provides a useful tool for inducing the selective deletion of genes that are essential for proper development and enables the study of gene functions in properly...
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Utility of Radial Probe Endobronchial Ultrasound Guided Transbronchial Lung Biopsy in Bronchus Sign Negative Peripheral Pulmonary Lesions

Hong KS, Lee KH, Chung JH, Shin KC, Jin HJ, Jang JG, Ahn JH

Background: The presence of the bronchus sign on chest computed tomography is associated with an increased diagnostic yield of radial probe endobronchial ultrasound– guided transbronchial lung biopsy (RP-EBUS-TBLB). However, the...
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Machine Learning Approaches to Identify Factors Associated with Women's Vasomotor Symptoms Using General Hospital Data

Ryu KJ, Yi KW, Kim YJ, Shin JH, Hur JY, Kim T, Seo JB, Lee KS, Park H

Background: To analyze the factors associated with women's vasomotor symptoms (VMS) using machine learning. Methods: Data on 3,298 women, aged 40–80 years, who attended their general health check-up from January 2010...
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Multicenter, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of a Controlled-release, Once-daily UIC201609/UIC201610 Combination Therapy for Functional Dyspepsia: Preliminary Study

Lee JW, Youn YH, Choi SC, Lee KJ, Kim N

Background/Aims: Functional dyspepsia is a disease involving a range of upper gastrointestinal symptoms derived from various pathophysiologies. Tablets containing a combination of rabeprazole and controlled-release (CR) mosapride were recently developed. To...
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Comparison between Gasless and Gas-Inflated Robot-Assisted NippleSparing Mastectomy

Lee H, Lee J, Lee K, Kim JY, Park HS

Purpose: Nipple-sparing mastectomy (NSM) includes various techniques, including conventional or endoscopic mastectomies. Since the introduction of robot-assisted NSM (RANSM) in 2015, 2 main methods have been used: gasless and gas-inflated...
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2021 Korean Society of Myocardial Infarction Expert Consensus Document on Revascularization for Acute Myocardial Infarction

Chang K, Ahn Y, Lim S, Yang JH, Lee KY, Choo EH, Kim HK, Nam CW, Kim W, Hwang JY, Rha SW, Kim HS, Cho MC, Jang Y, Jeong MH, tTFoECDotKSoMI(

Acute myocardial infarction (AMI) is a fatal manifestation of ischemic heart disease and remains a major public health concern worldwide despite advances in its diagnosis and management. The characteristics of...
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Correlation between Severity of Synovitis and Clinical Features in Rotator Cuff Tears

Lee D, Lee KH, Jo YH, Joo IH, Lee HJ, Jeong SY, Lee BG

Background: Rotator cuff tears can be asymptomatic in some cases; however, even when the tear size is small, clinical symptoms can be very severe. This suggests that symptoms of rotator...
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Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea

Heo GB, Kye SJ, Sagong M, Lee EK, Lee KN, Lee YN, Choi KS, Lee MH, Lee YJ

In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they...
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Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells

Choi YK, Kang JI, Hyun JW, Koh YS, Kang JH, Hyun CG, Yoon KS, Lee KS, Lee CM, Kim TY, Yoo ES, Kang HK

Alopecia is a distressing condition caused by the dysregulation of anagen, catagen, and telogen in the hair cycle. Dermal papilla cells (DPCs) regulate the hair cycle and play important roles...
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Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation

Lim CJ, Hong K, Lee JM, Han ES, Hong SK, Choi Y, Yi NJ, Lee KW, Suh KS

Backgrounds/Aims: Biliary complications continue to be the major morbidity and mortality causes following living donor liver transplantation (LT). Endoscopic retrograde cholangiopancreatography (ERCP) has been performed to identify the biliary leakage...
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Kaposi Sarcoma-Like Lesions Caused by Candida guilliermondii Infection in a Kidney Transplant Patient

Kim SJ, Shin JM, Lee KW, Kim YS, Rao B, Lee Y

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Restoration of implant-supported fixed dental prosthesis using the automatic abutment superimposition function of the intraoral scanner in partially edentulous patients

Park KW, Park JM, Lee KW

The digital workflow of optical impressions by the intraoral scanner and CADCAM manufacture of dental prostheses is actively developing. The complex process of traditional impression taking, definite cast fabrication, wax...
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Efficacy and Safety of DWJ1252 Compared With Gasmotin in the Treatment of Functional Dyspepsia: A Multicenter, Randomized, Double-blind, Active-controlled Study

Park JH, Lee KN, Lee OY, Choi MG, Chung H, Choi SC, Kim N, Park H, Sung IK, Sohn CI, Jee SR, Jang JY, Rhee PL, Park MI, Kwon JG, Park KS, Lee KJ, Lee JS

  • KMID: 2510066
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):87-96.
  • doi: 10.5056/jnm20061
Background/Aims Prokinetics such as mosapride citrate CR (conventional-release; Gasmotin) are commonly used in functional dyspepsia (FD). This study aims to evaluate the efficacy and safety of once-a-day mosapride citrate SR (DWJ1252),...
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Comparison of calcium-channel blockers for longterm clinical outcomes in patients with vasospastic angina

Kim SE, Jo SH, Han SH, Lee KY, Her SH, Lee MH, Seo WW, Cho SS, Baek SH

Background/Aims: Calcium channel blockers (CCBs) are the most widely prescribed medication for patients with vasospastic angina (VA). However, few studies have compared the prognosis of VA patients who are prescribed...
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Genotypic characterization of fluoroquinolone-resistant Escherichia coli isolates from edible offal

Son SH, Seo KW, Kim YB, Noh EB, Lee KW, Oh TH, Kim SJ, Song JC, Kim TW, Lee YJ

Abstract: Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics...
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Clinical and Radiological Outcomes after Various Treatments of Midshaft Clavicle Fractures in Adolescents

Kim HY, Yang DS, Bae JH, Cha YH, Lee KW, Choy WS

Background: Controversy exists about the optimal treatment of midshaft clavicle fractures in the presence of significant displacement, comminution, or shortening of the fracture in adolescents. The purpose of this study...
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Clinical Outcome of Arthroscopic Partial Repair of Large to Massive Posterosuperior Rotator Cuff Tears: Medialization of the Attachment Site of the Rotator Cuff Tendon

Lee KW, Lee GS, Yang DS, Park SH, Chun YS, Choy WS

Background: The goal of this study was to evaluate the clinical and radiological outcomes of arthroscopic partial repair with medialization of the attachment site of the rotator cuff tendon and...
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Artificial Intelligence Approaches to Social Determinants of Cognitive Impairment and Its Associated Conditions

Lee KS, Park KW

Background and Purpose: This study uses an artificial-intelligence model (recurrent neural network) for evaluating the following hypothesis: social determinants of disease association in a middle-aged or old population are different...
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