Korean J Med.  2016 Jan;90(1):50-54. 10.3904/kjm.2016.90.1.50.

Lupus-like Glomerulonephritis Associated with Extranodal Marginal Zone B-cell Lymphoma of MALT

Affiliations
  • 1Department of Internal Medicine, Seoul Medical Center, Seoul, Korea. kmy008@hamnail.net
  • 2Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Korea.
  • 3Department of Pathology, Hankook Kidney and Diabetes Institute, Seoul, Korea.

Abstract

Lupus-like glomerulonephritis is an immune complex disease with features of lupus nephritis in the absence of systemic lupus erythematosus (SLE). We report a 49-year-old man diagnosed with lupus-like glomerulonephritis associated with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). He was admitted to the hospital for edema. At admission, the serum creatinine was 2.2 mg/dL and the urine protein level was 3.9 mg/day. A renal biopsy showed features of lupus nephritis with no clinical or serological evidence of SLE. Extranodal marginal zone B-cell lymphoma of MALT was discovered concurrently. After successful chemotherapy, the lupus-like glomerulonephritis and lymphoma entered complete remission.

Keyword

Lupus nephritis; Glomerulonephritis; Lymphoma; Non-Hodgkin

MeSH Terms

Biopsy
Creatinine
Drug Therapy
Edema
Glomerulonephritis*
Humans
Immune Complex Diseases
Lupus Erythematosus, Systemic
Lupus Nephritis
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Middle Aged
Creatinine
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