J Korean Neurosurg Soc.  2007 Sep;42(3):220-223.

Dural Marginal Zone Lymphoma Confused with Meningioma en Plaque

Affiliations
  • 1Department of Neurosurgery, School of Medicine, Eulji University, Daejeon, Korea. nsksm@eulji.ac.kr

Abstract

We report a case of dural marginal zone lymphoma which showed the usual radiological findings resembling meningioma. A 59-year-old woman presented with headache. Initial computed tomography and magnetic resonance images showed a frontal convexity meningioma. The patient underwent a craniotomy and subtotal (simpson grade II) resection of tumor was done. Pathological examination confirmed an extranodal marginal zone B-cell lymphoma of Mucosa-Associated Lymphoid Tissue (MALT). The lesion was composed of a lymphoid mass with irregularly shaped follicles surrounded by many monomorphic small lymphocytes and a stained marginal zone for B-cell markers CD20 and CD29a. The natural history of primary CNS lymphoma and MALT type lymphoma are different. B-cell MALT lymphoma can mimic meningioma in its radiological features. Accordingly, MALT lymphoma of the CNS must be considered in the differential diagnosis of meningioma.

Keyword

B-cell lympoma of MALT; Meningioma

MeSH Terms

B-Lymphocytes
Craniotomy
Diagnosis, Differential
Female
Headache
Humans
Lymphocytes
Lymphoid Tissue
Lymphoma*
Lymphoma, B-Cell, Marginal Zone
Meningioma*
Middle Aged
Natural History
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