Korean J Perinatol.
2007 Jun;18(2):163-167.
A Case of Pregnancy in Essential Thrombocythaemia with Low dose Aspirin Treatment
- Affiliations
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- 1Department of Obstetrics and Gynecology, SAM An-Yang Hospital, An-Yang, Korea. kobgy@hanmail.net
Abstract
- Essential thrombocythaemia (ET) is a chronic myeloproliferative disorder characterized by markedly elevated platelet count in the peripheral blood due to an excessive proliferation of bone marrow megakaryocytes. The pregnancy outcome among patients with ET is mostly successful but adverse outcome due to thrombotic and bleeding complications is a matter of concern: miscarriage, intrauterine growth retardation, abruptio placenta, intrauterine fetal death and preterm delivery. Various treatments such as acetylsalicylic acid, hydroxyurea, anagrelide, heparin, interferon alpha and plateletpheresis have been proposed to improve the pregnancy outcome. We report a case of pregnant woman in condition of ET who succeeded in normal vaginal delivery without specific obstetric complications after low dose aspirin therapy during pregnancy.
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