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Human platelet lysate efficiency, stability, and optimal heparin concentration required in culture of mammalian cells

Mohamed HE, Asker ME, Kotb NS, El Habab A

BACKGROUND: Fetal bovine serum (FBS) has been used to support the growth and proliferation of mammalian cells for decades. Owing to several risk factors associated with FBS, several trials have...
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Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus?

Fashami MA, Hajian S, Afrakhteh , Khoob MK

OBJECTIVE: Gestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis of GDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatory...
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What are the most important predictive factors for clinically relevant posthepatectomy liver failure after right hepatectomy for hepatocellular carcinoma?

Navarro JG, Yang SJ, Kang I, Choi GH, Han DH, Kim KS, Choi JS

PURPOSE: The risk of posthepatectomy liver failure (PHLF) after right hepatectomy remains substantial. Additional parameters such as computed tomography volumetry, liver stiffness measurement by FibroScan, indocyanine green retention rate at...
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Platelet count is associated with sustained virological response rates in treatments for chronic hepatitis C

Jun BG, Park EJ, Lee WC, Jang JY, Jeong SW, Kim YD, Cheon GJ, Cho YS, Lee SH, Kim HS, Lee YN, Kim SG, Kim YS, Kim BS

BACKGROUND/AIMS: This study was conducted to clarify the sustained virological response (SVR) prediction ability of baseline and treatment-related factors in patients with chronic hepatitis C virus (HCV) infection. METHODS: This retrospective...
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Long-Term Efficacy and Safety of Partial Splenic Embolization in Hepatocellular Carcinoma Patients with Thrombocytopenia Who Underwent Transarterial Chemoembolization

Kim NH, Kim HJ, Cho YK, Hong HP, Kim BI

BACKGROUND: Performing transarterial chemoembolization (TACE) is difficult with the occurrence of thrombocytopenia in cirrhotic patients with hepatocellular carcinoma (HCC). We aimed to evaluate the long-term efficacy and safety of partial...
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Comparative analysis of unperforated and perforated appendicitis in laboratory values of patients who visited emergency center

Cho D, Seo JY

OBJECTIVE: Unperforated and perforated acute appendicitis need to be differentiated because appendicitis with a free perforation requires an emergency operation to prevent contamination inside the bowel from spreading into the...
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Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome

Yoo JR, Kim SH, Kim YR, Lee KH, Oh WS, Heo ST

BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not...
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Tocilizumab-induced Thrombocytopenia in Patients with Rheumatoid Arthritis

Lee JS, Oh JS, Hong S, Lee CK, Yoo B, Kim YG

OBJECTIVE: Interlukin-6 (IL-6) increases platelet count during inflammation and may act in a manner similar to thrombopoietin. Tocilizumab is a monoclonal antibody of the IL-6 receptor and widely used in...
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Evaluation of Noninvasive Liver Fibrosis Blood Markers in Patients with Chronic Hepatitis B and Hepatitis C

Lee JH, Cho J, Kim J, Uh Y, Youn KJ

BACKGROUND: Liver fibrosis evaluation is an important issue in chronic liver disease patients. We aimed to develop noninvasive liver fibrosis biomarkers based on transient elastography (TE, FibroScan®) through retrospective review...
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The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases

Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD

The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states. PLR has been extensively examined in...
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Characteristics of blood tests in patients with acute cerebral infarction who developed symptomatic intracranial hemorrhage after intravenous administration of recombinant tissue plasminogen activator

Lee C, Na JU, Lee JH, Han SK, Choi PC, Lee YH, Park SO, Shin DH

OBJECTIVE: Patients suspected as having acute ischemic stroke usually undergo blood tests, including coagulation-related indexes, because thrombocytopenia and coagulopathy are contraindications for recombinant tissue plasminogen activator (rtPA) administration. We aimed...
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Comparison of acute phase reactant levels of Kawasaki disease patients who visited with less than 5 days duration of fever and with 5 days or longer

Do HJ, Jeong JH, Kim DH, Kim TY, Kang C, Lee SH, Lee SB

PURPOSE: Kawasaki disease (KD) is a common, acute systemic vasculitis in children. Acute phase reactants (APRs) have been used to assist diagnosis, and to predict outcome in children with KD....
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Myeloproliferative Neoplasm in Newly Diagnosed Acute Ischemic Stroke Patients

Chang MH, Lee JE, Lee MY, Kim KH

OBJECTIVE: Myeloproliferative neoplasm (MPN) is considered as one of the risk factors of ischemic stroke. Some MPN patients manifest stroke as their first symptom. Our purpose was to assess diagnostic...
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Portal pressure gradient and serum albumin: A simple combined parameter associated with the appearance of ascites in decompensated cirrhosis treated with transjugular intrahepatic portosystemic shunt

Zhao D, Zhang G, Wang M, Zhang C, Li J

BACKGROUND/AIMS: In recent years, greater assessment accuracy after transjugular intrahepatic portosystemic shunt (TIPS) to ascertain prognosis has become important in decompensated cirrhosis due to portal hypertension. The aim of this...
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Association between Medical Costs and the ProVent Model in Patients Requiring Prolonged Mechanical Ventilation

Roh J, Shin MJ, Jeong ES, Lee K

BACKGROUND: The purpose of this study was to determine whether components of the ProVent model can predict the high medical costs in Korean patients requiring at least 21 days of...
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Risk factors for the occurrence and persistence of coronary aneurysms in Kawasaki disease

Jeon SK, Kim G, Ko H, Byun JH, Lee HD

PURPOSE: Prognostic factors of coronary aneurysms in Kawasaki disease have been investigated in many studies. The aim of this study was to identify risk factors associated with early and late...
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Multicenter Retrospective Risk Assessment of Esophageal Variceal Bleeding in Patients with Cirrhosis: An Acoustic Radiation Force Impulse Elastography-Based Prediction Model

Heo JY, Kim BK, Park JY, Kim DY, Ahn SH, Tak WY, Kweon YO, Han KH, Park SY, Kim SU

BACKGROUND/AIMS: Acoustic radiation force impulse (ARFI) elastography predicts the presence of esophageal varices (EVs). We investigated whether an ARFI-based prediction model can assess EV bleeding (EVB) risk in patients with...
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Annual Report of the Korean Association of External Quality Assessment Service on Routine Hematology (2018)

Lee YK, Kim YM, Routine Hematology Program, Korean Association of External Quality Assessment Service

Two trials were conducted with proficiency tests for complete blood cell count (CBC) and blood cell morphology as part of the 2018 Routine Hematology Program of the Korean Association of...
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A Case of Hemostatic Disorder Due to Thrombocytopenia Caused by a Type B Dialysis Reaction

Kim BK, Lee JH

The biocompatibility of dialysis membranes has significantly reduced adverse responses to dialysis, such that nowadays they are rarely reported. We report the case of a patient diagnosed and subsequently treated...
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Factors prognostic of ruptured hepatocellular carcinoma presenting to the emergency department

Lee SH, Kim JS, Yu GN, Kim YJ, Ryoo SM, Sohn CH, Kim WY, Ahn S

OBJECTIVE: This study assessed whether characteristics of ruptured hepatocellular carcinoma (HCC) at presentation to the emergency department (ED) affect patient outcomes, and evaluated factors prognostic of HCC, particularly treatment modalities. METHODS:...
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