Korean J Pediatr.  2008 Jun;51(6):640-645. 10.3345/kjp.2008.51.6.640.

Clinical manifestations patterns of allergic disease in Korean children under the age of 6: multi-center study

Affiliations
  • 1Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea. bypyun@hosp.sch.ac.kr
  • 2Department of Pediatrics, College of Medicine, Konkuk University, Seoul, Korea.
  • 3Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea.
  • 4Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea.

Abstract

PURPOSE: It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress.
METHODS
Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire.
RESULTS
A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease.
CONCLUSION
In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

Keyword

Allergic march; Questionnaire; Multicenter study

MeSH Terms

Asthma
Child
Dermatitis, Atopic
Early Diagnosis
Fathers
Female
Hospitals, University
Humans
Hypersensitivity
Korea
Male
Parents
Surveys and Questionnaires
Rhinitis
Rhinitis, Allergic, Perennial
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