Korean J Otorhinolaryngol-Head Neck Surg.  2010 Dec;53(12):798-801. 10.3342/kjorl-hns.2010.53.12.798.

A Case of Bilateral Sensorineural Hearing Loss after Salicylate Intoxication

• Lee HN
• Kang WS
• Song HY
• Chung JW

• KMID: 2277180
• DOI: http://doi.org/10.3342/kjorl-hns.2010.53.12.798

Abstract

Salicylates, such as aspirin, are considered the most commonly used medicine in Korea for its anti-inflammatory, anti-pyretic, and analgesic properties. In spite of its wide range of benefits, aspirin produces unwanted adverse effects such as mucosal bleeding in the gastrointestinal tract, renal and hepatic dysfunction, Reye's syndrome in children, and hypersensitivity reactions, etc. Aspirin can also induce ototoxicity, such as reversible hearing loss and tinnitus. The pattern of hearing loss is typically mild to moderate and bilaterally flat in the absence of preexisting hearing loss. Hearing usually recovers in 72 hours after medication. However, it's rare that salicylate-induced ototoxicity are encountered. So we present this case of bilateral hearing loss that occurred after salicylate intoxication with a review of relevant literature.

Keyword

Sodium salicylate; Hearing loss; Inner ear; Poisoning

MeSH Terms

Aspirin
Child
Ear, Inner
Gastrointestinal Tract
Hearing
Hearing Loss
Hearing Loss, Bilateral
Hearing Loss, Sensorineural
Hemorrhage
Humans
Hypersensitivity
Korea
Reye Syndrome
Salicylates
Sodium Salicylate
Tinnitus
Aspirin
Salicylates
Sodium Salicylate