Korean J Obes.  2015 Mar;24(1):44-50. 10.7570/kjo.2015.24.1.44.

Decreased Intermuscular Adipose Tissue due to Caloric Restriction in Obese Korean Women

• Park JS
• Lee HO
• Kim YS
• Yim JE

• KMID: 2271152
• DOI: http://doi.org/10.7570/kjo.2015.24.1.44

Abstract

BACKGROUND
This study investigated the effects of caloric restriction on thigh intermuscular adipose tissue (IMAT) and the associations of IMAT and metabolic risk factors.
METHODS
Thirty-three obese Korean women (BMI 27.2+/-2.5 kg/m2; 32.3+/-8.7 years) were tested before and after 12 weeks of 354.7 kcal/day dietary caloric restriction: waist circumference (WC); %fat according to bioimpedence; subcutaneous adipose tissue (SAT); visceral adipose tissue (VAT); IMAT using single-slice CT scans at the levels of L4/L5 and mid-thigh (midpoint between the anterior iliac crest and patella); fasting levels of leptin, glucose, insulin, triglycerides, total-C, LDL-C, HDL-C, and HOMA-IR. Paired t-test and Spearman correlation analysis were performed.
RESULTS
WC, %fat, leptin, glucose, total-C, abdominal SAT and VAT, and mid-thigh IMAT decreased (P<0.05), and %change in mid-thigh IMAT correlated with %change in HOMA-IR (P<0.05).
CONCLUSION
Caloric restriction decreased the mid-thigh IMAT in obese Korean women, which may be correlated with reduction of metabolic risk.

Keyword

Caloric restriction; Intermuscular adipose tissue (IMAT); Obesity

MeSH Terms

Adipose Tissue*
Caloric Restriction*
Fasting
Female
Glucose
Humans
Insulin
Intra-Abdominal Fat
Leptin
Obesity
Risk Factors
Subcutaneous Fat
Thigh
Tomography, X-Ray Computed
Triglycerides
Waist Circumference
Glucose
Insulin
Leptin
Triglycerides