Brain Neurorehabil.  2012 Sep;5(2):47-51. 10.12786/bn.2012.5.2.47.

Movement Disorders after Traumatic Brain Injury

  • 1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea.


Traumatic brain injury can cause movement disorders such as tremor, dystonia, myoclonus, parkinsonism and chorea. After the severe traumatic brain injury, movement disorders have been reported in 13 to 66% of patients and 20% of cases combined with weakness, spasticity, cognitive impairment and ataxia. Postural/kinetic tremor, which is the most common type of movement disorder after traumatic brain injury, may be transient or persistent however the other syndromes tend to persist and produce significant impairment in activity of daily living. The symptomatic relief can generally be achieved with medical treatment and some cases with neurosurgical intervention such as functional stereotactic surgery or deep brain stimulation. This article reviews the epidemiology, underlying mechanism, the type and treatment of movement disorders follow traumatic brain injury.


dystonia; movement disorders; parkinsonism; traumatic brain injury; tremor

MeSH Terms

Brain Injuries
Deep Brain Stimulation
Movement Disorders
Muscle Spasticity
Parkinsonian Disorders


1. Jankovic J. Post-traumatic movement disorders: central and peripheral mechanisms. Neurology. 1994. 44:2006–2014.
2. Factor SA, Sanchez Ramos J, Weiner WJ. Trauma as an etiology of parkinsonism: a historical review of the concept. Mov Disord. 1988. 3:30–36.
3. O'Suilleabhain P, Dewey RB Jr. Movement disorders after head injury: diagnosis and management. J Head Trauma Rehabil. 2004. 19:305–313.
4. Monday K, Jankovic J. Psychogenic myoclonus. Neurology. 1993. 43:349–352.
5. Scarano VR, Jankovic J. Post-traumatic movement disorders: effect of the legal system on outcome. J Forensic Sci. 1998. 43:334–339.
6. Costeff H, Groswasser Z, Goldstein R. Long-term follow-up review of 31 children with severe closed head trauma. J Neurosurg. 1990. 73:684–687.
7. Krauss JK, Trnkle R, Kopp KH. Post-traumatic movement disorders in survivors of severe head injury. Neurology. 1996. 47:1488–1492.
8. Krauss JK, Trnkle R, Kopp KH. Posttraumatic movement disorders after moderate or mild head injury. Mov Disord. 1997. 12:428–431.
9. Boto GR, Lobato RD, Rivas JJ, Gomez PA, de la Lama A, Lagares A. Basal ganglia hematomas in severely head injured patients: clinicoradiological analysis of 37 cases. J Neurosurg. 2001. 94:224–232.
10. Kampfl A, Franz G, Aichner F, Pfausler B, Haring HP, Felber S, Luz G, Schocke M, Schmutzhard E. The persistent vegetative state after closed head injury: clinical and magnetic resonance imaging findings in 42 patients. J Neurosurg. 1998. 88:809–816.
11. Halliwell B. Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to parkinson's disease, alzheimer's disease, traumatic injury or stroke? Acta Neurol Scand Suppl. 1989. 126:23–33.
12. Boyeson MG, Jones JL, Harmon RL. Sparing of motor function after cortical injury. A new perspective on underlying mechanisms. Arch Neurol. 1994. 51:405–414.
13. Krauss JK, Wakhloo AK, Nobbe F, Trnkle R, Mundinger F, Seeger W. Lesion of dentatothalamic pathways in severe post-traumatic tremor. Neurol Res. 1995. 17:409–416.
14. Krauss JK, Mohadjer M, Nobbe F, Mundinger F. The treatment of posttraumatic tremor by stereotactic surgery. Symptomatic and functional outcome in a series of 35 patients. J Neurosurg. 1994. 80:810–819.
15. Krauss JK, Jankovic J. Head injury and posttraumatic movement disorders. Neurosurgery. 2002. 50:927–939.
16. Ellison PH. Propranolol for severe post-head injury action tremor. Neurology. 1978. 28:197–199.
17. Harmon RL, Long DF, Shirtz J. Treatment of post-traumatic midbrain resting-kinetic tremor with combined levodopa/carbidopa and carbamazepine. Brain Inj. 1991. 5:213–218.
18. Jacob PC, Pratap Chand R. Posttraumatic rubral tremor responsive to clonazepam. Mov Disord. 1998. 13:977–978.
19. Fox JL, Kurtzke JF. Trauma-induced intention tremor relieved by stereotaxic thalamotomy. Arch Neurol. 1966. 15:247–251.
20. Taira T, Speelman JD, Bosch DA. Trajectory angle in stereotactic thalamotomy. Stereotact Funct Neurosurg. 1993. 61:24–31.
21. Richardson RR. Rehabilitative neurosurgery: posttraumatic syndromes. Stereotact Funct Neurosurg. 1989. 53:105–112.
22. Reese R, Herzog J, Falk D, Lapw-tzen U, Pinsker MO, Mehdorn HM, Ebersbach G, Deuschl G, Volkmann J. Successful deep brain stimulation in a case of posttraumatic tremor and hemiparkinsonism. Mov Disord. 2011. 26:1954–1955.
23. Lee MS, Rinne JO, Ceballos Baumann A, Thompson PD, Marsden CD. Dystonia after head trauma. Neurology. 1994. 44:1374–1378.
24. Krauss JK, Mohadjer M, Braus DF, Wakhloo AK, Nobbe F, Mundinger F. Dystonia following head trauma: a report of nine patients and review of the literature. Mov Disord. 1992. 7:263–272.
25. Maki Y, Akimoto H, Enomoto T. Injuries of basal ganglia following head trauma in children. Childs Brain. 1980. 7:113–123.
26. Jankovic J, Brin MF. Therapeutic uses of botulinum toxin. N Engl J Med. 1991. 324:1186–1194.
27. Doder M, Jahanshahi M, Turjanski N, Moseley IF, Lees AJ. Parkinson's syndrome after closed head injury: a single case report. J Neurol Neurosurg Psychiatry. 1999. 66:380–385.
28. Bhatt M, Desai J, Mankodi A, Elias M, Wadia N. Posttraumatic akinetic-rigid syndrome resembling parkinson's disease: a report on three patients. Mov Disord. 2000. 15:313–317.
29. Roberts GW, Allsop D, Bruton C. The occult aftermath of boxing. J Neurol Neurosurg Psychiatry. 1990. 53:373–378.
30. Lampert PW, Hardman JM. Morphological changes in brains of boxers. JAMA. 1984. 251:2676–2679.
31. Krauss JK, Borremans JJ, Nobbe F, Mundinger F. Ballism not related to vascular disease: a report of 16 patients and review of the literature. Parkinsonism Relat Disord. 1996. 2:35–45.
32. King RB, Fuller C, Collins GH. Delayed onset of hemidystonia and hemiballismus following head injury: a clinicopathological correlation. Case report. J Neurosurg. 2001. 94:309–314.
33. Krauss JK, Mundinger F. Functional stereotactic surgery for hemiballism. J Neurosurg. 1996. 85:278–286.
34. Demirkiran M, Jankovic J. Paroxysmal dyskinesias: clinical features and classification. Ann Neurol. 1995. 38:571–579.
35. Biary N, Singh B, Bahou Y, al Deeb SM, Sharif H. Posttraumatic paroxysmal nocturnal hemidystonia. Mov Disord. 1994. 9:98–99.
36. Loher TJ, Krauss JK, Burgunder JM, Taub E, Siegfried J. Chronic thalamic stimulation for treatment of dystonic paroxysmal nonkinesigenic dyskinesia. Neurology. 2001. 56:268–270.
37. Siemers E, Pascuzzi R. Posttraumatic tic disorder. Mov Disord. 1990. 5:183.
38. Singer C, Sanchez Ramos J, Weiner WJ. A case of posttraumatic tic disorder. Mov Disord. 1989. 4:342–344.
39. Ranjan N, Nair KP, Romanoski C, Singh R, Venketswara G. Tics after traumatic brain injury. Brain Inj. 2011. 25:629–633.
40. Krauss JK, Jankovic J. Tics secondary to craniocerebral trauma. Mov Disord. 1997. 12:776–782.
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