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Clinical and Imaging Profile of Patients with Joubert Syndrome

Surisetti BK, Holla VV, Prasad S, Neeraja K, Kamble N, Yadav R, Pal PK

Objective Joubert syndrome (JS) is a rare syndrome characterized by ataxia and the molar tooth sign (MTS) on imaging. The present study aims to explore the clinical and radiological features...
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Effect of Varenicline on Tardive Dyskinesia: A Pilot Study

Caroff SN, Gutman AR, Northrop J, Leong SH, Berkowitz RM, Campbell EC

Objective: Although evidence implicates striatal cholinergic impairment as a mechanism underlying tardive dyskinesia, trials of nonspecific cholinergic agents have been inconclusive. As a partial agonist at specific nicotinic receptor subtypes,...
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Patient Knowledge, Attitude and Perceptions towards Botulinum Toxin Treatment for Movement Disorders in India

Mol TN, Kamble N, Holla VV, Mahale R, Pal PK, Yadav R

Objective There is limited literature on the knowledge, attitude, and perceptions (KAP) of botulinum toxin (BoNT) treatment among patients and caregivers. The objective of this study was to assess the...
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Telemedicine in an Academic Movement Disorders Center during COVID-19

Esper CD, Scorr L, Papazian S, Bartholomew D, Esper GJ, Factor SA

Objective Telemedicine has rapidly gained momentum in movement disorder neurology during the coronavirus disease (COVID-19) pandemic to preserve clinical care while mitigating the risks of in-person visits. We present data...
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The Genetic Relationship between Paroxysmal Movement Disorders and Epilepsy

Ahn H, Ko TS

Seizures and movement disorders both involve abnormal movements and are often difficult to distinguish due to overlapping phenomenology and possible etiological commonalities. Paroxysmal movement disorders, which include three paroxysmal dyskinesias...
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No Evidence of a Contribution of the Vestibular System to Frequent Falls in Progressive Supranuclear Palsy

Goldschagg N, Bremova-Ertl T, Bardins S, Dinca N, Feil K, Krafczyk S, Lorenzl S, Strupp M

BACKGROUND AND PURPOSE: Conflicting results about vestibular function in progressive supranuclear palsy (PSP) prompted a systematic examination of the semicircular canal function, otolith function, and postural stability. METHODS: Sixteen patients with...
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Oromandibular Dystonia: Demographics and Clinical Data from 240 Patients

Slaim L, Cohen M, Klap P, Vidailhet , Perrin A, Brasnu D, Ayache D, Mailly M

OBJECTIVE: To report demographic data from a large cohort of patients with oromandibular dystonia (OMD). METHODS: This is a retrospective review of patients with OMD referred to our institution between 1989...
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A Novel Homozygous Variant of SETX Causes Ataxia with Oculomotor Apraxia Type 2

Tariq H, Imran R, Naz S

BACKGROUND AND PURPOSE: Autosomal recessive cerebellar ataxias constitute a highly heterogeneous group of neurodegenerative disorders. This study was carried out to determine the clinical and genetic causes of ataxia in...
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A Novel c.826G>A Mutation in a Boy with Allan-Herndon-Dudley Syndrome: Clinical Significance of Thyroid Function Tests in Developmental Delay of Unknown Origin

Shin EK, Park BH, Moon JH, Kim JH, Yoo HW, Kim GH

Allan-Herndon-Dudley syndrome (AHDS) is an X-linked intellectual disability caused by monocarboxylate transporter 8 (MCT8) deficiency. AHDS manifests in global developmental delay, axial hypotonia, quadriplegia, movement disorders in male patients, and...
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Aripiprazole-induced Tardive Dyskinesia in 13 Years Old Girl Successfully Treated with Biperiden: A Case Report

Lamberti M, Di Rosa G, Cucinotta , Pironti E, Galati C, Gagliano A

In the last years second-generation antipsychotics are increasingly prescribed in the pediatric population for the treatment of several psychiatric disorders. Among the long term adverse effects, extrapyramidal symptoms (EPS) are...
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Paroxysmal Kinesigenic Dyskinesia as the Presenting and Only Manifestation of Multiple Sclerosis after Eighteen Months of Follow-Up

Baguma M, Ossemann M

Other than tremor, movement disorders are uncommon in multiple sclerosis. Among these uncommon clinical manifestations, paroxysmal kinesigenic dyskinesia is the most frequently reported. It is characterized by episodic attacks of...
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Tardive Dyskinesia Associated with Bupropion

Tuman TC, Çakır U, Yıldırım O, Camkurt MA

Present report describes a 46 year old male patient with a diagnosis of major depression who developed tardive dyskinesia during bupropion therapy. Our patient had no history of neuroleptic use...
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A Systematic Review of the Effectiveness of Medical Cannabis for Psychiatric, Movement and Neurodegenerative Disorders

Lim K, See YM, Lee J

The discovery of endocannabinoid’s role within the central nervous system and its potential therapeutic benefits have brought forth rising interest in the use of cannabis for medical purposes. The present...
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Psychodynamic Psychotherapy for Functional (Psychogenic) Movement Disorders

Sharma VD, Jones R, Factor SA

OBJECTIVE: As the literature for the treatment of functional (psychogenic) movement disorders (FMD) is sparse, we assessed clinical outcomes in patients with FMD who underwent treatment with psychodynamic psychotherapy (PDP). METHODS:...
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Applications of CRISPR/Cas9 for Gene Editing in Hereditary Movement Disorders

Im W, Moon J, Kim M

Gene therapy is a potential therapeutic strategy for treating hereditary movement disorders, including hereditary ataxia, dystonia, Huntington's disease, and Parkinson's disease. Genome editing is a type of genetic engineering in...
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Movement Disorders Following Cerebrovascular Lesions: Etiology, Treatment Options and Prognosis

Kwon DY

Post-stroke movement disorders are uncommon, but comprise an important part of secondary movement disorders. These exert variable and heterogeneous clinical courses according to the stroke lesion and its temporal relationships....
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Successful Management of Tardive Dyskinesia with Quetiapine and Clonazepam in a Patient of Schizophrenia with Type 2 Diabetes Mellitus

Mohapatra

Tardive dyskinesia is one of the most significant side effects of antipsychotic medications. Antipsychotic treated schizophrenia patients with diabetes mellitus are more likely to develop tardive dyskinesia than those without...
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Movement Disorders in Non-Wilsonian Cirrhotic Patients: A Report of the Prevalence and Risk Factors from a Study Done in a Medical School in an Agricultural-Based Community

Methawasin K, Chonmaitree P, Wongjitrat C, Rattanamongkolgul S, Asawavichienjinda T

OBJECTIVE: Parkinsonism and other movement disorders have previously been reported in the acquired hepatocerebral degeneration associated with portosystemic shunting. However, there is no study to date about their prevalence as...
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Gait Analysis in Cervical Spondylotic Myelopathy

Nishimura , Endo K, Suzuki H, Tanaka H, Shishido T, Yamamoto K

STUDY DESIGN: Gait analysis of patients with cervical spondylotic myelopathy (CSM) by using a sheet-type gait analysis system. PURPOSE: The aim of this study was to compare the gait patterns of...
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A Case of Aripiprazole Induced Tardive Dyskinesia in a Neuroleptic-Naive Patient with Two Years of Follow Up

Goyal R, Devi SH

  • KMID: 2171133
  • Clin Psychopharmacol Neurosci.
  • 2014 Apr;12(1):69-71.
Tardive dyskinesia (TD) is arguably the most serious and potential irreversible side effect of antipsychotic medication. Traditionally first generation antipsychotics are the neuroleptics considered to have higher risk of TD...
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