Korean J Nutr.  2006 Dec;39(8):728-732.

Effects of Corn Peptide Consumption on Plasma Lipid Profiles in Cholesterol-Fed Rats

• Moon MS
• Lee JH
• Lee MS
• Kwun IS
• Chung YI
• Lee DH
• Kim Y

Abstract

In this study, the effects of corn peptide consumption on plasma lipid profiles were investigated in high cholesterol dietfed rats. Male Sprague-Dawley rats (n = 21) were fed with corn peptide-free (control) diet, diets containing 2% or 5% corn peptide for 5 weeks. Hypercholesterolemia was induced by adding 1% cholesterol and 0.5% cholic acid to all diets. No difference was found in food intake and body weight gain among groups. The corn peptide treated groups showed significant improvement in the plasma level of HDL-cholesterol (p < 0.05) compared to the control group, while the plasma total cholesterol and LDL-cholesterol were not affected. 5% corn peptide supplemented diet reduced plasma level of triglycerides (p < 0.05). The atherogenic index was decreased in the corn peptide treated groups. These results suggest that consumption of corn peptide may lead to an amelioration of metabolic syndrome as well as a reduction of cardiovascular disease and hyperlipidemia through increasing the level of HDL-cholesterol, and decreasing the level of triglycerides in plasma.

Keyword

corn peptide; lipid profiles; rat; cardiovascular disease

MeSH Terms

Animals
Body Weight
Cardiovascular Diseases
Cholesterol
Cholic Acid
Diet
Eating
Humans
Hypercholesterolemia
Hyperlipidemias
Male
Plasma*
Rats*
Rats, Sprague-Dawley
Triglycerides
Zea mays*
Cholesterol
Cholic Acid
Triglycerides