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Cardiac Complications Associated with Eating Disorders in Children: A Multicenter Retrospective Study

Choi SY, Lee KJ, Kim SC, Lee EH, Lee YM, Kim YB, Yi DY, Kim JY, Kang B, Jang HJ, Hong SJ, Choi YJ, Kim HJ

Purpose: Eating disorders often result in somatic complications, including cardiac abnormalities. Cardiac abnormalities may involve any part of the heart, including the cardiac conduction system, and can lead to sudden...
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Generation and Application of Directly Reprogrammed Endothelial Cells

Jung C, Oh JE, Lee S, Yoon Ys

Cell-based therapy has emerged as a promising option for treating advanced ischemic cardiovascular disease by inducing vascular regeneration. However, clinical trials with adult cells turned out disappointing in general. As...
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Effects of Short-term Spinning Exercise on Vascular Function in Young Women

Kim YW, Jae SY, Cho MJ, Kim HJ

Purpose: Regular aerobic exercise has been recommended as an effective lifestyle strategy for the prevention and treatment of cardiovascular disease. However, it is unclear whether short-term exercise (< 6 weeks)...
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The Triglyceride-Glucose Index Can Predict Long-Term Major Adverse Cardiovascular Events in Turkish Patients With High Cardiovascular Risk

Hayıroğlu M, Çınar T, Çiçek V, Palice A, Ayhan G, Tekkeşin A

Objective: There is an evidence gap regarding the predictive accuracy of the triglycerideglucose (TyG) index for long-term major adverse cardiovascular events (MACEs) in individuals with high cardiovascular risk. The aim...
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Low-Density Lipoprotein Cholesterol Level, Statin Use and Myocardial Infarction Risk in Young Adults

Jeong H, Han K, Yoo SJ, Kim MK

Objective: The consequences of blood lipid abnormalities for cardiovascular disease risk in young adults is unclear. Optimal lipid levels may also vary depending on whether a statin drug is taken....
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Beneficial Role of Vitamin D on Endothelial Progenitor Cells (EPCs) in Cardiovascular Diseases

Sen A, Vincent V, Thakkar H, Abraham R, Ramakrishnan L

Cardiovascular diseases (CVDs) are the leading cause of death in the world. Endothelial progenitor cells (EPCs) are currently being explored in the context of CVD risk. EPCs are bone marrow...
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Fibrotic Burden Determines Cardiovascular Risk among Subjects with Metabolic Dysfunction-Associated Fatty Liver Disease

Han E, Lee Yh, Lee JS, Lee HW, Kim BK, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Kim SU

Background/Aims: Metabolic dysfunction associated fatty liver disease (MAFLD) has recently been introduced to compensate for the conventional concept of nonalcoholic fatty liver disease (NAFLD). We explored whether fibrotic burden determines...
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Lipoprotein Lipase: Is It a Magic Target for the Treatment of Hypertriglyceridemia

Moon JH, Kim K, Choi SH

High levels of triglycerides (TG) and triglyceride-rich lipoproteins (TGRLs) confer a residual risk of cardiovascular disease after optimal low-density lipoprotein cholesterol (LDL-C)–lowering therapy. Consensus has been made that LDL-C is...
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High Cardiorespiratory Fitness Protects against Molecular Impairments of Metabolism, Heart, and Brain with Higher Efficacy in Obesity-Induced Premature Aging

Pantiya P, Thonusin C, Sumneang N, Ongnok B, Chunchai T, Kerdphoo S, Jaiwongkam T, Arunsak B, Siri-Angkul N, Sriwichaiin S, Chattipakorn N, Chattipakorn SC

Background: High cardiorespiratory fitness (CRF) protects against age-related diseases. However, the mechanisms mediating the protective effect of high intrinsic CRF against metabolic, cardiac, and brain impairments in non-obese versus obese...
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Long-Term Outcomes of Congenital Adrenal Hyperplasia

Nordenström A, Lajic S, Falhammar H

A plethora of negative long-term outcomes have been associated with congenital adrenal hyperplasia (CAH). The causes are multiple and involve supra-physiological gluco- and mineralocorticoid replacement, excess adrenal androgens both intrauterine...
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Cardiovascular diseases in HIV patients

Chang HH

New and more effective antiretroviral therapy regimens have increased viral suppression and improved immune function recovery, leading to the extension of the lifespan of people living with HIV (PLWH). The...
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New, Novel Lipid-Lowering Agents for Reducing Cardiovascular Risk: Beyond Statins

Kim K, Ginsberg HN, Choi SH

Statins are the cornerstone of the prevention and treatment of atherosclerotic cardiovascular disease (ASCVD). However, even under optimal statin therapy, a significant residual ASCVD risk remains. Therefore, there has been...
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Association between obesity and COVID-19

Lim S

Background: Since December 2019, most countries have struggled with the novel coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). During the coronavirus disease-2019 (COVID-19) pandemic, weight gain became prevalent because the preventive...
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Does nonalcoholic fatty liver disease predispose patients to carotid arteriosclerosis and ischemic stroke?

Jin Q, Yang RX, Fan JG

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Male Infertility Increases the Risk of Cardiovascular Diseases: A Nationwide Population-Based Cohort Study in Taiwan

Chen PC, Chen YJ, Yang CC, Lin TT, Huang CC, Chung CH, Sun CA, Chien WC

Purpose: Some evidence suggests that male infertility increases the risk of cardiovascular diseases (CVDs). However, the evidence in Asian populations is relatively scarce. The aim of this study is to...
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Metabolic Dysfunction-Associated Fatty Liver Disease Better Predicts Incident Cardiovascular Disease

Jeong S, Oh YH, Choi S, Chang J, Kim SM, Son JS, Lee G, Kim W, Park SM

Background/Aims: Metabolic dysfunction (MD)-associated fatty liver disease is a new positive diagnostic criterion based on hepatic steatosis and MD. However, a comprehensive evaluation on the association of MD and hepatic...
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Maintaining Physical Activity Is Associated with Reduced Major Adverse Cardiovascular Events in People Newly Diagnosed with Diabetes

Kim D, Seo J, Ha KH, Kim DJ

Background: We investigated the association between changes in physical activity and the risk of a major adverse cardiovascular event (MACE) in people with newly diagnosed diabetes. Methods: Using a nationwide database,...
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Triglyceride–Glucose Index Predicts Cardiovascular Outcome in Metabolically Unhealthy Obese Population: A Nationwide Population-Based Cohort Study

Cho YK, Kim HS, Park JY, Lee WJ, Kim YJ, Jung CH

Background: This study assesses the prognostic value of the triglyceride–glucose (TyG) index for cardiovascular (CV) risk in subgroups based on metabolic health and obesity status. Methods: Originally, 514,866 participants were enrolled...
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Improvement in Age at Mortality and Changes in Causes of Death in the Population with Diabetes: An Analysis of Data from the Korean National Health Insurance and Statistical Information Service, 2006 to 2018

Han E, Song SO, Kim HS, Son KJ, Jee SH, Cha BS, Lee BW

Background: Diabetes is a leading cause of death that is responsible for 1.6 million annual deaths worldwide. However, the life expectancy and age at death of people with diabetes have...
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Extra-Glycemic Effects of Anti-Diabetic Medications: Two Birds with One Stone?

Rhee EJ

The world is suffering from a rapid increase in the number of people with diabetes due to the increased prevalence of obesity and lengthened life span. Since the development of...
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