Korean J Med.
2014 Dec;87(6):750-755. 10.3904/kjm.2014.87.6.750.
Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma
- Affiliations
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- 1Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. mlee@kuh.ac.kr
- 2Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- 3Department of Laboratoy Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- KMID: 2269375
- DOI: http://doi.org/10.3904/kjm.2014.87.6.750
Abstract
- Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.
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