Korean J Med.  2015 Aug;89(2):142-148. 10.3904/kjm.2015.89.2.142.

Helicobacter Pylori Infection and Related Gastrointestinal Diseases

• Bang CS
• Baik GH

• KMID: 2269022
• DOI: http://doi.org/10.3904/kjm.2015.89.2.142

Abstract

Helicobacter pylori is among the most common bacterial pathogens, but it has not yet been conquered. It is related to various gastrointestinal diseases, including chronic gastritis, peptic ulcer, gastric marginal zone B cell lymphoma, and gastric cancer. The association between Helicobacter pylori infection and functional dyspepsia or gastroesophageal reflux disease is not clear. Numerous factors determine disease course and outcome, such as bacterial virulence, genotype, host immunity, and environmental factors. The eradication of Helicobacter pylori in associated gastrointestinal diseases is important for the treatment and prevention of recurrent or severe outcomes, especially in Korea where gastric cancer is prevalent.

Keyword

Helicobacter pylori; Gastritis; Peptic ulcer; Stomach neoplasms; Gastroesophageal reflux

MeSH Terms

Dyspepsia
Gastritis
Gastroesophageal Reflux
Gastrointestinal Diseases*
Genotype
Helicobacter pylori*
Helicobacter*
Korea
Lymphoma, B-Cell, Marginal Zone
Peptic Ulcer
Stomach Neoplasms
Virulence