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Evaluations of Gastric Acid Pocket Using Novel Vertical 8-Channel pH Monitoring System and Effects of Acid Secretion Inhibitors

Sumi S, Ishimura N, Mikami H, Okimoto E, Tamagawa Y, Mishiro T, Kinoshita Y, Ishihara S

  • KMID: 2517531
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):370-376.
  • doi: 10.5056/jnm20115
Background/Aims The gastric acid pocket has an important role in gastroesophageal reflux disease development. In this study, we utilized a novel 8-channel pH monitoring system with sensor intervals of 1 cm...
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The Usefulness of the Measurement of Esophagogastric Junction Distensibility by EndoFLIP in the Diagnosis of Gastroesophageal Reflux Disease

Lee JM, Yoo IK, Kim E, Hong SP, Cho JY

Background/Aims: Increased esophagogastric junction (EGJ) relaxation is the most important mechanism involved in gastroesophageal reflux disease (GERD). An endoscopic functional luminal imaging probe (EndoFLIP Ⓡ ) is a device used...
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The Role of Combined Multichannel Intraluminal Impedance-pH Monitoring in Infants with Brief, Resolved, Unexplained Events

Pavić I, Navratil M, Bosanac M, Fureš JS, Jureković II, Hojsak I

Purpose: Data on the relationship between gastroesophageal reflux (GER) and brief resolved unexplained events (BRUE) in infants is scarce. The aim of this study was to identify the characteristics of...
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Efficacy of S-pantoprazole 10 mg in the Symptom Control of Non-erosive Reflux Disease: A Phase III Placebo-controlled Trial

Cho YK, Choi MG, Park H, Kim JW, Lee DH, Ko KH, Kim SG, Jung HY, Hong SJ, Lee YC, Lee SH

  • KMID: 2514680
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):223-230.
  • doi: 10.5056/jnm19053
Background/Aims S-isomer (S) pantoprazole is more bioavailable and less dependent on cytochrome 2C19 than is racemic pantoprazole. We aim to evaluate the efficacy and safety of 10 mg S-pantoprazole for treatment...
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Simultaneous Evaluation of Laryngopharyngeal Reflux and Swallowing Function Using Hypopharyngeal Multichannel Intraluminal Impedance Measurements in Neurologically Impaired Patients

Masui D, Fukahori S, Hashizume N, Ishii S, Higashidate N, Sakamoto S, Tsuruhisa S, Nakahara H, Saikusa N, Tanaka Y, Yagi M

  • KMID: 2514677
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):198-204.
  • doi: 10.5056/jnm20125
Background/Aims This study aims to evaluate the presence of laryngopharyngeal reflux (LPR) and to investigate the use of hypopharyngeal baseline impedance (BI) for assessing swallowing dysfunction and gastroesophageal reflux disease (GERD)...
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Impact of Overlapping Functional Gastrointestinal Disorders on the Quality of Life in Patients With Gastroesophageal Reflux Disease

Lee SW, Chang CS

  • KMID: 2514674
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):176-184.
  • doi: 10.5056/jnm19006
Gastroesophageal reflux disease (GERD) and functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome and functional dyspepsia, are common afflictions within the general population. Both conditions have a considerable impact on...
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A Systematic Review and Meta-analysis of Randomized Control Trials: Combination Treatment With Proton Pump Inhibitor Plus Prokinetic for Gastroesophageal Reflux Disease

Jung DH, Huh CW, Lee SK, Park JC, Shin SK, Lee YC

  • KMID: 2514673
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):165-175.
  • doi: 10.5056/jnm20161
Background/Aims Prokinetics can be used for treating patients with gastroesophageal reflux disease (GERD), who exhibit suboptimal response to proton pump inhibitor (PPI) treatment. We conducted a systematic review to assess the...
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Usefulness of Endoscopic Hill Grade in Evaluating Children Suspected of Having Gastroesophageal Reflux Disease

Yoo IH, Joo JY, Yang HR

  • KMID: 2514676
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):191-197.
  • doi: 10.5056/jnm20033
Background/Aims This study aim to evaluate the relationship between the Hill grade confirmed by esophagogastroduodenoscopy (EGD) and the degree of gastroesophageal reflux (GER) by 24-hour multichannel intraluminal impedance-pH monitoring (MII-pH) in...
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Characteristics of Symptomatic Belching in Patients With Belching Disorder and Patients Who Exhibit Gastroesophageal Reflux Disease With Belching

Jeong SO, Lee JS, Lee TH, Hong SJ, Cho YS, Park J, Jeon SR, Kim HG, Kim JO

  • KMID: 2514681
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):231-239.
  • doi: 10.5056/jnm20114
Background/Aims Belching disorder (BD) is clinically distinct from gastroesophageal reflux disease (GERD) with belching. Supragastric belching (SGB) is closely associated with reflux episodes. This study investigates belch characteristics in association with...
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The Influence of Gastroesophageal Reflux Disease on Daytime Sleepiness and Depressive Symptom in Patients With Obstructive Sleep Apnea

Kang HH, Lim CH, Oh JH, Cho MJ, Lee SH

  • KMID: 2514679
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):215-222.
  • doi: 10.5056/jnm20071
Background/Aims As there is insufficient evidence for a relationship between gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA), we investigated whether OSA diagnosed by polysomnography (PSG) is related to GERD. Methods A...
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The Impact of Erosive Reflux Esophagitis on the Decline of Lung Function in the General Population

Kang HR, Lee YJ, Lee HY, Park TY, Lee JK, Heo EY, Chung HS, Choi SH, Kim DK

Background: The impact of reflux esophagitis on the decline of lung function has been rarely reported. This study was performed to evaluate the association between erosive reflux esophagitis and lung...
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Association of Gastroesophageal Reflux Disease with Preterm Birth: Machine Learning Analysis

Lee KS, Kim ES, Kim Dy, Song IS, Ahn KH

Background: This study used machine learning and population data for testing the associations of preterm birth with gastroesophageal reflux disease (GERD) and periodontitis. Methods: Retrospective cohort data came from Korea National...
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Patients With Definite and Inconclusive Evidence of Reflux According to Lyon Consensus Display Similar Motility and Esophagogastric Junction Characteristics

Ribolsi M, Savarino E, Rogers B, Rengarajan A, Coletta MD, Ghisa M, Cicala M, Gyawali CP

  • KMID: 2521157
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):565-573.
  • doi: 10.5056/jnm20158
Background/Aims The role of esophageal high-resolution manometry (HRM) within Lyon consensus phenotypes, especially patients with inconclusive gastroesophageal reflux disease (GERD) evidence, has not been fully investigated. In this multicenter, observational study...
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Clinical Characteristics of Esophageal Motility Disorders in Patients With Heartburn

Takahashi S, Matsumura T, Kaneko T, Tokunaga M, Oura H, Ishikawa T, Nagashima A, Shiratori W, Akizue N, Ohta Y, Kikuchi A, Fujie M, Saito K, Okimoto K, Maruoka D, Nakagawa T, Arai M, Kato J, Kato N

  • KMID: 2521155
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):545-554.
  • doi: 10.5056/jnm20131
Background/Aims Esophageal motility disorders (EMDs) contribute to the pathophysiology of gastroesophageal reflux disease. However, the causes of EMDs and their impact on gastroesophageal reflux disease-associated symptoms remain unknown. This study aims...
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Esophageal Nocturnal Baseline Impedance and Post-reflux Swallow-induced Peristaltic Wave Index in Identifying Proton Pump Inhibitor-refractory Non-erosive Reflux Disease

Wang Y, Ye B, Wang M, Lin L, Jiang L

  • KMID: 2521152
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):525-532.
  • doi: 10.5056/jnm20073
Background/Aims Esophageal mean nocturnal baseline impedance (MNBI) levels and post-reflux swallow-induced peristaltic wave (PSPW) index could increase the diagnostic value of 24-hour multichannel intraluminal impedance and pH monitoring in patients with...
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2020 Seoul Consensus on the Diagnosis and Management of Gastroesophageal Reflux Disease

Jung HK, Tae CH, Song KH, Kang SJ, Park JK, Gong EJ, Shin JE, Lim HC, Lee SK, Jung DH, Choi YJ, Seo SI, Kim JS, Lee JM, Kim BJ, Kang SH, Park CH, Choi SC, Kwon JG, Park KS, Park MI, Lee TH, Kim SY, Cho YS, Lee HH, Jung KW, Kim DH, Moon HS, Miwa H, Chen CL, Gonlachanvit S, Ghoshal UC, Wu JCY, Siah KTH, Hou X, Oshima T, Choi MY, Lee KJ, TKSoNaM

  • KMID: 2521147
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):453-481.
  • doi: 10.5056/jnm21077
Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate into the esophagus or beyond, resulting in either troublesome symptoms or complications. GERD is heterogeneous in terms of...
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The Effect of Bariatric Surgery and Endoscopic Procedures on Gastroesophageal Reflux Disease

Fass OZ, Mashimo H

  • KMID: 2510060
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):35-45.
  • doi: 10.5056/jnm20169
Obesity is a global epidemic posing a significant burden on patients and healthcare systems. Gastroesophageal reflux disease is associated with obesity and its prevalence is also growing worldwide. Numerous bariatric...
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Acid Exposure Time > 6% Might Not Improve the Therapeutic Outcome in Chinese Gastroesophageal Reflux Disease Patients

Lin Y, Li Y, Liang M, Tan N, Zhang M, Chen S, Xiao Y

  • KMID: 2510062
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):55-62.
  • doi: 10.5056/jnm19219
Background/Aims There is less acid burden in Chinese gastroesophageal reflux disease (GERD) patients. However, the Lyon consensus proposed a higher threshold of acid exposure time (AET > 6%) for GERD. The...
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Comparison of Short Versus Long Esophageal Myotomy in Cases With Idiopathic Achalasia: A Randomized Controlled Trial

Nabi Z, Ramchandani M, Sayyed M, Chavan R, Darisetty S, Goud R, Murthy HVV, Reddy DN

  • KMID: 2510063
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):63-70.
  • doi: 10.5056/jnm20022
Background/Aims Per-oral endoscopic myotomy (POEM) is an established treatment for achalasia. The technique of POEM is still evolving and the impact of length of esophageal myotomy on the outcomes of POEM...
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Endoscopic Prediction for Acid Reflux in Patients without Hiatus Hernia

Kim JY, Shin IS, Min YW, Kim K, Lee H, Min BH, Lee JH, Kim JJ, Rhee PL

Background/Aims: A diagnosis of gastroesophageal reflux disease is challenging in patients who have reflux symptoms but do not respond to proton pump inhibitors nor have reflux esophagitis and hiatal hernia...
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Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr