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circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition

Liang Q, Chu F, Zhang L, Jiang Y, Li L, Wu H

Background/Aims: Chemoresistance is a common event after cancer chemotherapy, which is associated with the deregulation of circular RNAs (circRNAs). The objective of this study was to clarify the role of...
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LINC00562 drives gastric cancer development by regulating miR-4636–AP1S3 axis

Xu L, Liu D, Wang X

Dysregulation of certain long non-coding RNAs may facilitate tumor initiation and progression. However, numerous carcinogenesis-related long non-coding RNAs have not been characterized. The goal of this study was to elucidate...
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The prognostic value of tumor budding in gastric adenocarcinomas: A cross-sectional study

Baydas T, Coban G, Besiroglu M, Simsek M, Shbair AT, Topcu A, Yasin AI, Seker M, Turk HM

Background: Tumor budding is a negative prognostic factor for many solid malignancies. We investigated the relationship between patients’ clinicopathological characteristics and tumor budding, as well as the effect of budding...
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Risk of Metabolic Syndrome and Fatty Liver Diseases in Gastric Cancer Survivors: A Propensity Score-Matched Analysis

Han SJ, Baik SJ, Yoon YH, Kim JH, Lee HS, Jeon S, Park H

Background/Aims: To investigate the risk of metabolic syndrome and fatty liver diseases in gastric cancer survivors compared to non-cancer subjects. Methods: The data from the health screening registry of the Gangnam...
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Approach for the Management of Indefinite-for-neoplasia Lesions Detected on Gastric Mucosal Biopsy

Ryu DG, Choi CW

Indefinite-for-neoplasia is an expression used to describe lesions in which carcinoma or dysplasia cannot be clearly and conclusively established via biopsy. Gastric indefinite-for-neoplasia may represent a reactive change secondary to...
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Impact of Body Mass Index on Survival Depending on Sex in 14,688 Patients with Gastric Cancer in a Tertiary Hospital in South Korea

Jo HH, Kim N, Jang J, Choi Y, Park J, Park YM, Ahn S, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH

Background/Aims: The incidence and prognosis of gastric cancer (GC) shows sex difference. This study aimed to evaluate the effect of body mass index (BMI) on GC survival depending on sex. Methods: The...
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Clinical outcomes of gastric cancer surgery after liver transplantation

Kim S, Lee HJ, Alzahrani F, Kim J, Kim SH, Kim S, Cho YS, Park JH, Lee JM, Kong SH, Park DJ, Suh KS, Yang HK

Purpose: De novo malignancy is common after liver transplantation (LT); however, there are limited reports on the clinical outcomes of gastric cancer surgery after LT. Our study aimed to investigate...
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Association between soy products, fruits, vegetables, and dairy products and gastric cancer risk in Helicobacter pylori-infected subjects: a case-control study in Korea

Kwak JH, Eun CS, Han DS, Kim YS, Song KS, Choi BY, Kim HJ

BACKGROUND/OBJECTIVES: Consumption of certain protective foods may help inhibit Helicobacter pylori (H. pylori) associated gastric pathologies. However, studies conducted to assess the efficacy of protective foods in H. pylori-infected subjects...
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Korean Practice Guidelines for Gastric Cancer 2022: An Evidence-based, Multidisciplinary Approach

Kim TH, Kim IH, Kang SJ, Choi M, Kim BH, Eom BW, Kim BJ, Min BH, Choi CI, Shin CM, Tae CH, Gong Cs, Kim DJ, Cho AEH, Gong EJ, Song GJ, Im HS, Ahn HS, Lim H, Kim HD, Kim JJ, Yu JI, Lee JW, Park JY, Kim JH, Song KD, Jung M, Jung MR, Son SY, Park SH, Kim SJ, Lee SH, Kim TY, Bae WK, Koom WS, Jee Y, Kim YM, Kwak Y, Park YS, Han HS, Nam SY, Kong SH, on behalf of The Development Working Group for the Korean Practice Guidelines for Gastric Cancer 2022 Task Force Team

Gastric cancer is one of the most common cancers in Korea and the world. Since 2004, this is the 4th gastric cancer guideline published in Korea which is the revised...
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A Standardized Pathology Report for Gastric Cancer: 2nd Edition

Park YS, Kook MC, Kim Bh, Lee HS, Kang DW, Gu MJ, Shin OR, Choi Y, Lee W, Kim H, Song IH, Kim KM, Kim HS, Kang G, Park DY, Jin SY, Kim JM, Choi YJ, Chang HK, Ahn S, Chang MS, Han SH, Kwak Y, Seo AN, Lee SH, Cho MY, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago....
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A standardized pathology report for gastric cancer: 2nd edition

Park YS, Kook MC, Kim Bh, Lee HS, Kang DW, Gu MJ, Shin OR, Choi Y, Lee W, Kim H, Song IH, Kim KM, Kim HS, Kang G, Park DY, Jin SY, Kim JM, Choi YJ, Chang HK, Ahn S, Chang MS, Han SH, Kwak Y, Seo AN, Lee SH, Cho MY, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago....
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Comparison between laparoscopic pylorus-preserving gastrectomy and laparoscopic distal gastrectomy for overweight patients with early gastric cancer

Lee HJ, Alzahrani KM, Kim SR, Park JH, Suh YS, Park DJ, Lee HJ, Yang HK, Kong SH

Purpose: Laparoscopic pylorus-preserving gastrectomy (LPPG) has a nutritional advantage over laparoscopic distal gastrectomy (LDG), however, may be less beneficial in overweight patients in terms of weight loss. The purpose of...
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Molecular and Immune Profiling of Syngeneic Mouse Models Predict Response to Immune Checkpoint Inhibitors in Gastric Cancer

Lee D, Choi J, Oh HJ, Ham IH, Lee SH, Nomura S, Han SU, Hur H

Purpose Appropriate preclinical mouse models are needed to evaluate the response to immunotherapeutic agents. Immunocompetent mouse models have rarely been reported for gastric cancer. Thus, we investigated immunophenotypes and responses...
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A Pilot Study of Peritumor Administration of 5-FU for Preventing Bleeding in Advanced Gastric Cancer

Kim NH, Park JH, Koo DH, Jung YS, Yang JY, Lee HY

Five-FU is a potent chemotherapeutic agent for suppressing endothelial cell growth. The purpose of this study was to investigate the usefulness of local peritumor injection of 5-FU for patients with...
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Refeeding Syndrome after Gastrectomy in a Patient with Hypophosphatemia: A Case Report

Oh CA

This study describes an 81-year-old male who was highly suspicious for refeeding syndrome (RFS) after a retrospective review of his postoperative clinical progression. This highlights the importance of clinicians’ awareness...
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Body Compositions of Elderly and Non-Elderly Patients Following Gastrectomy for Gastric Cancer

Kang JH, Jung MR, Kim SE, Jeong O

Purpose: Radical gastric resection is the mainstay of treatment in gastric cancer. However, patients can suffer from eating restrictions, weight loss, and malnutrition after gastrectomy, to which elderly patients are...
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Development and Internal/External Validation of a Prediction Model for Weight Loss Following Gastric Cancer Surgery: A Multicenter Retrospective Study

Park JH, Kong SH, Park DJ, Yang HK, Kim JW, Park KB, Cho I, Hwang SH, Kim DW, Kim SM, Ryu SW, Gong SC, Jung PY, Ryu H, Kim SG, Choi CI, Kim DH, Choi SI, Park JH, Park DJ, Kim GY, Choi Y, Lee HJ

Purpose: To develop an individualized model for predicting the extent of unintentional weight loss following gastrectomy in patients with gastric cancer based on related risk factors and to externally validate...
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Clinical Role of Magnifying Endoscopy with Narrow-band Imaging in the Diagnosis of Early Gastric Cancer

Choi SI

Narrow-band imaging (NBI) is the most widely used image-enhanced endoscopic technique. The superficial microanatomy of gastric mucosa can be visualized when used with a magnifying endoscopy with narrow-band imaging (ME-NBI). The...
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A Case of Neovascular Glaucoma with Branch Retinal Vein Occlusion Accompanied by Severe Anemia

Kim HJ, Chey JH, Lee CK

Purpose: Here we report a case of neovascular glaucoma in a patient with branch retinal vein occlusion and severe anemia due to advanced gastric cancer. Case summary: A 79-year-old hypertensive male...
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Circ_0081143 Contributes to Gastric Cancer Malignant Development and Doxorubicin Resistance by Elevating the Expression of YES1 by Targeting mziR-129-2-3p

Ou W, Lin L, Chen R, Xu Q, Zhou C

Background/Aims: The increased mortality of gastric cancer (GC) is mainly attributed to the development of chemoresistance. Circular RNAs, as the novel type of biomarkers in GC, have attracted wide attention....
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