Korean J Med.
2015 Oct;89(4):452-456. 10.3904/kjm.2015.89.4.452.
A Case of Mycobacterium gordonae Pulmonary Disease in a Patient with Ulcerative Colitis Treated with Infliximab
- Affiliations
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- 1Department of Internal Medicine, Dankook University Hospital, Dankook University Medical College, Cheonan, Korea. jspark@dankook.ac.kr
- 2Department of Pathology, Dankook University Hospital, Dankook University Medical College, Cheonan, Korea.
- KMID: 2268980
- DOI: http://doi.org/10.3904/kjm.2015.89.4.452
Abstract
- Tumor necrosis factor-alpha (TNF-alpha) is a key component of the host defense against mycobacterial infection. Mycobacterium gordonae (M. gordonae) is one of the least virulent mycobacteria, and is generally considered non-pathogenic if detected from a clinical specimen. Here, we report a rare case of pulmonary M. gordonae infection in a patient with ulcerative colitis who had been treated with infliximab, a TNF-alpha antagonist. M. gordonae infection was treated successfully with clarithromycin, rifampin, and ethambutol. We believe this to be the first report of M. gordonae pulmonary disease associated with TNF-alpha antagonist treatment.
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