Korean J Med.  2013 Feb;84(2):158-167.

Common Infectious Diseases in Hematopoietic Stem Cell Transplant Recipients

• Lee DG

Abstract

Hematopoietic stem cell transplantation (HSCT) has improved the outcome of numerous malignant and non-malignant diseases. However, infectious diseases (IDs) still contributes the burden of morbidity and mortality significantly after both autologous and allogeneic HSCTs. IDs are usually classified by the time periods after HSCT; pre-engraftment period, immediate and late post-engraftment period. Kinds of IDs and their frequencies and distribution are dependent not only on the stem cell sources, conditioning regimens, presence of graft-versus-host diseases, but also on the region, prophylactic antibiotics, and so on. In this article, the common IDs after HSCT according to the time periods are reviewed. Additionally, it is tried to focus the recent Korean perspectives, for examples, tuberculosis, herpes zoster, respiratory virus infection-especially hope to be of help for the non-transplant specialists and/or primary physicians.

Keyword

Hematopoietic stem cell transplantation; Infectious diseases medicine; Opportunistic infections

MeSH Terms

Anti-Bacterial Agents
Communicable Diseases
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Herpes Zoster
Opportunistic Infections
Specialization
Stem Cells
Transplants
Tuberculosis
Viruses
Anti-Bacterial Agents