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Fecal Microbiota Transplantation for Treating Steroid-Refractory Acute Graft-versus-Host Disease of the Gut

Yeon SH, Lee MW, Jo DY, Heo BY, Kwon J, Song IC

Restoring the microbiota via fecal microbiota transplantation (FMT) can be an effective treatment for steroid-refractory acute graft-versus-host disease (GVHD) of the gut. Here, we report two adult patients who underwent...
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Risk Factors for Seizures after Hematopoietic Stem Cell Transplantation in Pediatric Hemato-Oncologic Patients: A Single Tertiary Center Study in the Republic of Korea

Moon JU, Lee JY, Lee JW, Chung NG, Cho B, Lee IG

Purpose: The aim of this study was to assess the incidence of seizures, clinical manifestations, and risk factors that could predict the occurrence of seizures after hematopoietic stem cell transplantation...
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Factors Affecting Fear of Cancer Recurrence in Hematopoietic Stem Cell Transplant Patients

Jo EJ, Kim S

Purpose: The purpose of this study was to identify the factors that influence the fear of cancer recurrence in the patients of hematopoietic stem cell transplants based on Simonelli’s theory...
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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control

Wang SM, Park SS, Park SH, Kim NY, Kang DW, Na HR, Bae YY, Lee JW, Han S, Lim HK

Objective: No previous study examined impact of dementia in the outcome of allogeneic hematopoietic stem cell transplantation (HSCT). We aimed to investigate overall survival (OS) of patients with dementia after...
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Drug use evaluation of opioid analgesics in pain management among patients with hematopoietic stem cell transplantation

Oh HJ, Hong SY, Jeong YM, Choi KS, Lee E, Lee E, Kim YJ, Bang SM

Background Hematopoietic stem cell transplantation (HSCT) patients usually experience mucositis, musculoskeletal pain associated with high-dose chemotherapy, radiation, post-HSCT infection, or graft-versus-host disease. Pain management is important for the patients’ quality of...
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Transfusion in RhD Mismatch Hematopoietic Stem Cell Transplantation

Kim D, Kim KH, Seo YH, Park PW, Ahn JY, Seo JY

In some cases, hematopoietic stem cell transplants (HSCT) show differences in the D antigen. In previous studies, there have been few cases of de novo anti-D alloimmunization, and even rarer...
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Is immunological recovery clinically relevant at 100 days after allogeneic transplantation?

Park J, Lim SH, Kim SH, Yun J, Kim CK, Lee SC, Won JH, Hong DS, Park SK

Background/Aims: Immune reconstitution following allogeneic hematopoietic stem cell transplantation (HSCT) is affected by multiple variables during the transplantation. Methods: We assessed the clinical factors contributing to immune function reconstitution at 100...
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Clinical impact of anti-thymocyte globulin on survival and graft-versus-host disease in patients undergoing human leukocyte antigen mismatched allogeneic stem cell transplantation

Kim T, Choi Y, Lee JH, Park S, Ahn JS, Moon JH, Shin HJ, Lee WS, Kim D, Lee HS

Background/Aims: Rabbit anti-thymocyte globulin (ATG) is usually incorporated in hematopoietic stem cell transplantation (HSCT) to reduce the incidence of graft-versus-host disease (GVHD). This study aimed to find optimal ATG doses...
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Health-related Quality of Life of Children and Adolescents after Hematopoietic Stem Cell Transplantation

Hwang YM, Bang KS

Purpose: This study aimed to determine the level of health-related quality of life (HRQoL) of children and adolescents who received hematopoietic stem cell transplantation (HSCT) and to examine factors influencing...
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Comparison of quality of life and depression between hematopoietic stem cell transplantation survivors and their spouse caregivers

Park S, Choi EK, Kim IR, Cho J, Jang JH

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is an exhausting process that impacts both the patient and caregiver. METHODS: This was a cross-sectional, HSCT survivor-spouse caregiver matching study to determine quality of...
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Efficacy of parenteral glutamine supplementation in adult hematopoietic stem cell transplantation patients

Cho YK, Hong SY, Jeon SJ, Namgung HW, Lee E, Lee E, Bang SM

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) patients need parenteral nutrition because of nausea, vomiting, and mucositis caused by conditioning regimens. The demand for glutamine increases during the HSCT period. We...
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Predictive Role of Circulating Immune Cell Subtypes Early after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia

Kim TW, Park SS, Lim JY, Min GJ, Park S, Jeon YW, Yahng SA, Shin SH, Lee SE, Yoon JH, Cho BS, Eom KS, Lee S, Kim HJ, Min CK

BACKGROUND AND OBJECTIVES: Cells of innate immunity normally recover in the first weeks to months after allogenenic hematopoietic stem cell transplantation (allo-HSCT). Their relevance in terms of graft-versus-host disease (GVHD)...
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Impact of Day 14 Peripheral Blood Chimerism after Allogeneic Hematopoietic Stem Cell Bone Transplantation on the Treatment Outcome of Non-Malignant Disease

Choi YB, Lee JW, Sung KW, Koo HH, Kim HJ, Yoo KH

BACKGROUND: The impact of early peripheral blood chimerism on the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We aimed to determine whether day 14 peripheral blood chimerism...
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Lung Ultrasound to Evaluate Invasive Fungal Diseases after Allogeneic Hematopoietic Stem Cell Transplantation

Raffaella , Lorenzo L, Elisabetta X, Andrea A, Sarah M, Fabio G, Daniela C, Maria Teresa LS, Consuelo C, Massimo B, Fabio C, Jacopo P

Invasive fungal diseases (IFDs) are a leading cause of infection-related-mortality after allogeneic hematopoietic stem cell transplantation (HSCT). In this prospective pilot study, we investigated the use of bedside lung ultrasound...
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Clinical Symptoms and Signs of Dry Eye Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Beak JU, Ha MJ, Yi R, Yoo YS, Kim HS, Na KS

PURPOSE: To identify the symptoms and signs of patients with dry eye disease (DED) after allogenic hematopoietic stem cell transplantation (HSCT) and analyze the correlations between these signs and symptoms. METHODS:...
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Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation

Seo HJ, Baek YG, Cho BS, Kim TS, Um YH, Chae JH

OBJECTIVE: This study aimed to assess the anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Eighty-seven adult patients with various hematologic diseases, who were scheduled to receive...
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Third-party regulatory T cells prevent murine acute graft-versus-host disease

Lim JY, Im KI, Song Y, Kim N, Nam YS, Jeon YW, Cho SG

BACKGROUND/AIMS: Adoptive therapy with regulatory T (Treg) cells to prevent graft-versus-host disease (GVHD) would benefit from a strategy to improve homing to the sites of inflammation following hematopoietic stem cell...
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Allogeneic hematopoietic stem cell transplantation in congenital hemoglobinopathies with myeloablative conditioning and rabbit anti-thymocyte globulin

Park BK, Kim HS, Kim S, Lee JW, Park YS, Jang PS, Chung NG, Jeong DC, Cho B

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapy for β-thalassemia major (TM) and sickle cell disease (SCD) in children. Graft-versus-host disease (GVHD) and treatment-related mortality (TRM) remain...
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Effects of Parenteral Nutrition in Pediatric Patients with Hematopoietic Stem Cell Transplantation

Lim SY, Jung MJ, Park JE, Kim JS, Kim SH, Lyu CJ, Son ES

PURPOSE: This study examined the effects of parenteral nutrition (PN) on the nutritional status, clinical improvement, and PN-related complications in pediatric patients who had undergone hematopoietic stem cell transplantation (HSCT). METHODS:...
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The Detailed Kinetics of Cytomegalovirus-specific T cell Responses after Hematopoietic Stem Cell Transplantation: 1 Year Follow-up Data

Bae S, Jung J, Kim SM, Kang YA, Lee YS, Chong YP, Sung H, Lee SO, Choi SH, Kim YS, Woo JH, Lee JH, Lee JH, Lee KH, Kim SH

The detailed kinetics of the cytomegalovirus (CMV)-specific T cell response in hematopoietic stem cell transplant (HCT) recipients have not yet been fully assessed. We evaluated these kinetics of CMV-specific T...
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