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Enumeration of CD34-positive Stem Cells Using the ADAMII Image-based Fluorescence Cell Counter

Yu H, Yoo J, Hwang JS, Kim M, Bae KH, Jekarl DW, Oh JH, Lee JY, Han S, Chung C, Kim M, Kim Y

BACKGROUND: It is very important to accurately enumerate CD34-positive (CD34+) cells for successful hematopoietic stem cell transplantation (HSCT). We evaluated the ability of the newly developed image based-immunofluorescence cell counter...
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Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series

Jung M, Sung IY, Ko EJ

Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation...
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Comparison of quality of life and depression between hematopoietic stem cell transplantation survivors and their spouse caregivers

Park S, Choi EK, Kim IR, Cho J, Jang JH

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is an exhausting process that impacts both the patient and caregiver. METHODS: This was a cross-sectional, HSCT survivor-spouse caregiver matching study to determine quality of...
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Successful engraftment after infusion of multiple low doses of CD34+ cells from a poorly matched sibling donor in a patient with severe aplastic anemia

Kum CD, Lee MJ, Park JE

The dose of CD34+ cells is known to influence the outcome of allogeneic peripheral blood stem cell (PBSC) and/or T-cell-depleted transplantation. A previous study proposed that 2×10⁶ CD34+ cells/kg is...
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Efficacy of parenteral glutamine supplementation in adult hematopoietic stem cell transplantation patients

Cho YK, Hong SY, Jeon SJ, Namgung HW, Lee E, Lee E, Bang SM

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) patients need parenteral nutrition because of nausea, vomiting, and mucositis caused by conditioning regimens. The demand for glutamine increases during the HSCT period. We...
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Predictive Role of Circulating Immune Cell Subtypes Early after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia

Kim TW, Park SS, Lim JY, Min GJ, Park S, Jeon YW, Yahng SA, Shin SH, Lee SE, Yoon JH, Cho BS, Eom KS, Lee S, Kim HJ, Min CK

BACKGROUND AND OBJECTIVES: Cells of innate immunity normally recover in the first weeks to months after allogenenic hematopoietic stem cell transplantation (allo-HSCT). Their relevance in terms of graft-versus-host disease (GVHD)...
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Late Complications of Allogenic Stem Cells Transplantation in Leukaemia

Kanagasundram S, Amini F

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can cure leukaemia. However, long term complications of post transplantation interfere with the patients’ full recovery. The objective of this review was to...
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Identifying Minimum Data Sets of Oral Mucous Integrity Assessment for Documentation Systematization

Kim MS, Jung HK, Kang MJ, Park NJ, Kim HH, Ryu JM

PURPOSE: The purpose of this study was to identify minimum data sets for oral mucous integrity-related documentation and to analyze nursing records for oral care. METHODS: To identify minimum data sets...
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Impact of Day 14 Peripheral Blood Chimerism after Allogeneic Hematopoietic Stem Cell Bone Transplantation on the Treatment Outcome of Non-Malignant Disease

Choi YB, Lee JW, Sung KW, Koo HH, Kim HJ, Yoo KH

BACKGROUND: The impact of early peripheral blood chimerism on the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We aimed to determine whether day 14 peripheral blood chimerism...
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Clinical significance of T cell receptor excision circle (TREC) quantitation after allogenic HSCT

Mikhael NL, Elsorady M

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a well-established treatment modality for a variety of diseases. Immune reconstitution is an important event that determines outcomes. The immune recovery of T...
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Lung Ultrasound to Evaluate Invasive Fungal Diseases after Allogeneic Hematopoietic Stem Cell Transplantation

Raffaella , Lorenzo L, Elisabetta X, Andrea A, Sarah M, Fabio G, Daniela C, Maria Teresa LS, Consuelo C, Massimo B, Fabio C, Jacopo P

Invasive fungal diseases (IFDs) are a leading cause of infection-related-mortality after allogeneic hematopoietic stem cell transplantation (HSCT). In this prospective pilot study, we investigated the use of bedside lung ultrasound...
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Clinical Symptoms and Signs of Dry Eye Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Beak JU, Ha MJ, Yi R, Yoo YS, Kim HS, Na KS

PURPOSE: To identify the symptoms and signs of patients with dry eye disease (DED) after allogenic hematopoietic stem cell transplantation (HSCT) and analyze the correlations between these signs and symptoms. METHODS:...
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A Boy with Chronic Active EBV Infection Presented as Mosquito Bite Hypersensitivity Progressed to Fatal Hemophagocytic Lymphohistiocytosis due to NK Cell Neoplasm

Lee JA, Han SB, Chung NG, Kang JH, Kim M, Jeong DC

Chronic active Epstein-Barr virus (CAEBV) infection is characterized by recurrent infectious mononucleosis (IM)-like symptoms and an unusual pattern of anti-EBV antibodies. We report a boy with CAEBV who progressed to...
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Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation

Seo HJ, Baek YG, Cho BS, Kim TS, Um YH, Chae JH

OBJECTIVE: This study aimed to assess the anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Eighty-seven adult patients with various hematologic diseases, who were scheduled to receive...
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Evaluation of Antiemetic Therapy for Breakthrough Nausea and Vomiting in Patients with Hematopoietic Stem Cell Transplantation

Kim J, Hong SY, Jeon SJ, Namgung HW, Lee ES, Lee E, Bang SM

BACKGROUND: The patients receiving hematopoietic stem cell transplantation (HSCT) are known to have a high incidence of breakthrough nausea and vomiting due to the conditioning regimen. The purpose of this...
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The Effects of Stress and Stress Coping on Life Quality in Cancer Patients and Caregivers: A Dyadic Analysis Using an Actor-Partner Interdependence Model

Kim EJ, Han JW

PURPOSE: This study is to determine actor and partner effects of stress coping on quality of life (QoL) of cancer patients and their primary caregivers using an actor-partner independence model...
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Storage and use of cord blood

Lee YH

Cord blood (CB) has been used as an important source for hematopoietic stem cell transplantation and has been stored in public CB banks (CBBs) worldwide since the mid-1990s. Recently, the...
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Third-party regulatory T cells prevent murine acute graft-versus-host disease

Lim JY, Im KI, Song Y, Kim N, Nam YS, Jeon YW, Cho SG

BACKGROUND/AIMS: Adoptive therapy with regulatory T (Treg) cells to prevent graft-versus-host disease (GVHD) would benefit from a strategy to improve homing to the sites of inflammation following hematopoietic stem cell...
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Effect of Oral Cryotherapy for Reducing Oral Mucositis in Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-analysis

Park SH, Han SH

PURPOSE: This systematic review and meta-analysis provided scientific evidence for oral cryotherapy as a nursing intervention for the prevention of Oral Mucositis (OM) associated with Hematopoietic Stem Cell Transplantation (HSCT). METHODS:...
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Clinical Risk Factors Influencing Dental Developmental Disturbances in Childhood Cancer Survivors

Kang CM, Hahn SM, Kim HS, Lyu CJ, Lee JH, Lee J, Han JW

PURPOSE: Although studies regarding dental developmental disturbances after childhood cancer treatment have increased, they have many limitations. Studies analyzing the significance of independent clinical risk factors with regard to the...
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