Soonchunhyang Med Sci.  2013 Dec;19(2):128-132.

Primary Cytomegalovirus Peritonitis Following Unrelated Hematopoietic Stem Cell Transplantation

• Park SK

Abstract

Cytomegalovirus (CMV) has emerged as a significant opportunistic pathogen in the era of immunosuppression. Among patients with hematopoietic stem cell transplantation (HSCT), CMV has become an increasingly important cause of gastrointestinal disease. Almost cases of CMV peritonitis are due to CMV colitis with or without bowel perforation. However, primary CMV peritonitis combined without CMV colitis is very rare. We report the first case of primary CMV peritonitis not accompanied by CMV colitis or bowel perforation in a patient who underwent allogeneic HSCT from unrelated donor. Diagnosis of primary CMV peritonitis was made by computed tomography of abdomen, colonoscopy, peritoneal biopsy, and real time reverse transcription-polymerase chain reaction for CMV. Thereafter, he was treated successfully with intravenous ganciclovir.

Keyword

Cytomegalovirus; Peritonitis; Stem cell transplantation

MeSH Terms

Abdomen
Biopsy
Colitis
Colonoscopy
Cytomegalovirus*
Diagnosis
Ganciclovir
Gastrointestinal Diseases
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells*
Humans
Immunosuppression
Peritonitis*
Stem Cell Transplantation
Unrelated Donors
Ganciclovir