- Clinical Experience of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients Aged 60 Years and Older in South Korea
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Ji YS, Ahn JS, Yun J, Jang GH, Lim SH, Kim SH, Kim CK, Won JH, Park SK
- KMID: 2538962
- Yonsei Med J.
- 2023 Feb;64(2):123-132.
- doi: 10.3349/ymj.2022.0331
Purpose: The purpose of this study is to share our outcomes and experiences on allogeneic hematopoietic stem cell transplantation (HSCT) in elderly patients aged 60 years and older with myelodysplastic... -
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- Efficacy and Safety of Human Bone Marrow-Derived Mesenchymal Stem Cells according to Injection Route and Dose in a Chronic Kidney Disease Rat Model
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Chae HK, Suh N, Jang MJ, Kim YS, Kim BH, Aum J, Shin HC, You D, Hong B, Park HK, Kim CS
- KMID: 2539622
- Int J Stem Cells.
- 2023 Feb;16(1):66-77.
- doi: 10.15283/ijsc21146
Background and Objectives: We compared the efficacy and safety of human bone marrow-derived mesenchymal stem cells (hBMSC), delivered at different doses and via different injection routes in an animal model... -
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- Busulfan, Melphalan, and Etoposide (BuME) Showed an Equivalent Effect to Busulfan, Cyclophosphamide, and Etoposide (BuCE) as Conditioning Therapy for Autologous Stem Cell Transplantation in Patients with Relapsed or High-Risk Non-Hodgkin’s Lymphoma: A Multicenter Randomized Phase II Study bythe Consortium for Improving Survival of Lymphoma (CISL)
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Kim KH, Lee JH, Lee M, Kim HG, Do YR, Park Y, Oh SY, Shin HJ, Kim WS, Park SK, Kong JH, Park MR, Yang DH, Kwak JY, Kang HJ, Mun YC, Won JH
- KMID: 2538013
- Cancer Res Treat.
- 2023 Jan;55(1):304-313.
- doi: 10.4143/crt.2022.004
Purpose High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is the standard management for relapsed or high-risk non-Hodgkin’s lymphoma (NHL). We reported the busulfan, melphalan, and etoposide (BuME) conditioning... -
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- Prognostic impact of total body irradiation dose in pediatric acute lymphoblastic leukemia patients treated with allogeneic hematopoietic stem cell transplantation in second complete remission
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Jang W, Jo S, Yoo JW, Kim S, Lee JW, Jang PS, Chung NG, Cho B
- KMID: 2537548
- Blood Res.
- 2022 Dec;57(4):256-263.
- doi: 10.5045/br.2022.2022174
Background Allogeneic HSCT may improve survival in pediatric ALL patients who relapse. In this study, we analyzed the outcome and prognostic factors of 62 ALL patients (35 male, 56.5%) who received... -
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- Reduced-intensity conditioning versus myeloablative conditioning allogeneic stem cell transplantation for patients with myelofibrosis
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Kim DH, Seo J, Shin DY, Koh Y, Hong J, Kim I, Yoon SS, Byun JM
- KMID: 2537549
- Blood Res.
- 2022 Dec;57(4):264-271.
- doi: 10.5045/br.2022.2022194
Background Allogeneic hematopoietic stem cell transplantation (alloSCT) is the sole curative option for myelofibrosis (MF). However, it is unknown as to which of the two, myeloablative conditioning (MAC) or reduced-intensity conditioning... -
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- How I Treat Primary Immune Deficiencies with Hematopoietic Stem Cell Transplantation
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Kook H, Kim B, Baek HJ
- KMID: 2534761
- Clin Pediatr Hematol Oncol.
- 2022 Oct;29(2):35-43.
- doi: 10.15264/cpho.2022.29.2.35
Primary immune deficiencies (PID), or more recently, inborn errors of immunity (IEI), resulting from genetic defects of the immune system may present with increased susceptibility to infections, persistent inflammation, and... -
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- Is It a Refractory Disease?- Fecal Incontinence; beyond Medication
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Lee C, Lee JL
- KMID: 2534747
- Ewha Med J.
- 2022 Oct;45(4):e9.
- doi: 10.12771/emj.2022.e9
Fecal incontinence (FI) is recurrent uncontrolled passage of fecal material in patients. The life expectancy of humans has increased. Elderly patients have a significant rate of FI. Therefore, the number... -
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- Outcome of Intensive Therapy for Children with Relapsed Acute Myeloid Leukemia: A Single Institution Korean Study
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Lee JW, Yoo JW, Kim S, Jang PS, Chung NG, Cho B
- KMID: 2534202
- Cancer Res Treat.
- 2022 Oct;54(4):1230-1239.
- doi: 10.4143/crt.2021.1011
Purpose Approximately 30%-40% of pediatric acute myeloid leukemia (AML) patients relapse. In this study, we analyzed the outcome and prognostic factors of relapsed AML patients who had previously received first-line... -
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- Treatment for relapsed acute promyelocytic leukemia: what is the best post-remission treatment?
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Min GJ, Cho BS, Park SS, Park S, Jeon YW, Yahng SA, Shin SH, Yoon JH, Lee SE, Eom KS, Kim YJ, Lee S, Min CK, Cho SG, Lee JW, Kim HJ
- KMID: 2533247
- Blood Res.
- 2022 Sep;57(3):197-206.
- doi: 10.5045/br.2022.2022060
Background Arsenic trioxide (ATO) is the standard treatment for relapsed acute promyelocytic leukemia (APL). However, consensus on post-remission therapies is still lacking. Methods We evaluated 52 patients who experienced relapse following initial treatment... -
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- Favorable outcomes with durable chimerism after hematopoietic cell transplantation using busulfan and fludarabine-based reduced-intensity conditioning for pediatric patients with hemophagocytic lymphohistiocytosis
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Suh JK, Koh YK, Kang SH, Kim H, Choi ES, Koh KN, Im HJ
- KMID: 2530881
- Blood Res.
- 2022 Jun;57(2):152-157.
- doi: 10.5045/br.2022.2022047
Background The incorporation of a reduced-intensity conditioning (RIC) regimen in hematopoietic cell transplantation (HCT) for patients with hemophagocytic lymphohistiocytosis (HLH) has decreased early mortality but is associated with a high rate... -
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- Isolated Breast Relapse of Early T-Cell Precursor Acute Lymphoblastic Leukemia after Stem Cell Transplantation: A Pediatric Case and Literature Review
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Kim BR, Baek HJ, Choi YJ, Lee YY, Kim J, Kook H
- KMID: 2529690
- Clin Pediatr Hematol Oncol.
- 2022 Apr;29(1):30-34.
- doi: 10.15264/cpho.2022.29.1.30
Extramedullary relapse in acute lymphoblastic leukemia (ALL) usually occurs in the central nervous system and testes those are known as sanctuary sites. Only a few cases of isolated breast relapse... -
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- Endoscopic balloon dilations for strictures of rectum, ileocecal valve and duodenum in a patient with X-linked inhibitor of apoptosis deficiency: a case report
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Otagiri S, Katsurada T, Sakurai K, Sugita J, Sakamoto N
- KMID: 2529574
- Intest Res.
- 2022 Apr;20(2):274-277.
- doi: 10.5217/ir.2021.00029
X-linked inhibitor of apoptosis (XIAP) deficiency is a rare primary immunodeficiency and gastrointestinal (GI) lesions in XIAP deficiency are similar to Crohn’s disease. For patients with Crohn’s disease, endoscopic balloon... -
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- Prophylaxis for invasive fungal infection in pediatric patients with allogeneic hematopoietic stem cell transplantation
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Perez P, Patiño J, Franco AA, Rosso F, Beltran E, Manzi E, Castro A, Estacio M, Valencia DM
- KMID: 2527495
- Blood Res.
- 2022 Mar;57(1):34-40.
- doi: 10.5045/br.2021.2021127
Background Antifungal prophylaxis is recommended for hematopoietic stem cell transplantation (HSCT) to decrease the incidence of invasive fungal infections (IFI). This study aimed to compare the two groups of antifungal prophylaxis... -
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- Comparison of Automated and Manual Gating of Lymphocyte Subsets in Hematopoietic Stem Cell Transplantation Recipients
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Lee H, Kim J, Lee J, Jung J, Oh EJ
- KMID: 2538578
- Lab Med Online.
- 2022 Jan;12(1):11-19.
- doi: 10.47429/lmo.2022.12.1.11
Background: Lymphocyte subset analysis is essential to evaluate the engraftment status in hematopoietic stem cell transplantation (HSCT). Automated gating tools are widely used for flow cytometry analysis. Unlike healthy individuals,... -
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- Influence of creatinine levels on survival in patients with veno-occlusive disease treated with defibrotide
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Kong SG, Lee JH, Lim YT, Lee JH, Eom HS, Lee H, Kim DY, Lim SN, Yoon SS, Kim SY, Lee HS
- KMID: 2524253
- Korean J Intern Med.
- 2022 Jan;37(1):179-189.
- doi: 10.3904/kjim.2021.178
Background/Aims: Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is one of the most fatal complications of hematopoietic cell transplantation (HCT), and defibrotide is the only curative drug. We conducted this study to... -
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- Changes in Serum Dickkopf-1, RANK Ligand, Osteoprotegerin, and Bone Mineral Density after Allogeneic Hematopoietic Stem Cell Transplantation Treatment
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Jang E, Ha J, Baek KH, Kang MI
- KMID: 2523490
- Endocrinol Metab.
- 2021 Dec;36(6):1211-1218.
- doi: 10.3803/EnM.2021.1248
Background: Dickkopf-1 (DKK1) regulates bone formation by inhibiting canonical Wnt/β-catenin pathway signaling, and indirectly enhances osteoclastic activity by altering the expression ratio of receptor activator of nuclear factor-κB ligand (RANKL)... -
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- Real-world Experience of Improvement in the Survival of Lymphoma and Myeloma Patients with Autologous Stem Cell Transplantation over a 25-year Period
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Cho H, Kim S, Lee K, Park JS, Suh C
- KMID: 2523032
- Korean J Med.
- 2021 Dec;96(6):501-511.
- doi: 10.3904/kjm.2021.96.6.501
Background/Aims: The first autologous peripheral blood stem cell transplantation (ASCT) in Korea was performed for a small-cell lung cancer patient at Asan Medical Center (AMC) in 1993. Recently, lymphoma and... -
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- Ruxolitinib for Treating Steroid-Refractory Acute Graft-Versus-Host Disease in an Infant with Malignant Osteopetrosis Who Received Double-Unit Umbilical Cord Blood Transplantation
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Jue JH, Shim YJ, Kim SA, Jung HR
- KMID: 2523697
- Keimyung Med J.
- 2021 Dec;40(2):119-124.
- doi: 10.46308/kmj.2021.00115
A 3-month-old male infant was transferred to our hospital due to bicytopenia. His bone marrow biopsy showed irregular bony trabeculae with cartilaginous core, which was consistent with osteopetrosis. In the... -
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- Prognostic factors of pediatric hematopoietic stem cell transplantation recipients admitted to the pediatric intensive care unit
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Kim DH, Ha EJ, Park SJ, Koh KN, Kim H, Im HJ, Jhang WK
- KMID: 2524322
- Acute Crit Care.
- 2021 Nov;36(4):380-387.
- doi: 10.4266/acc.2020.01193
Background: Pediatric patients who received hematopoietic stem cell transplantation (HSCT) tend to have high morbidity and mortality. While, the prognostic factors of adult patients received bone marrow transplantation were already... -
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- Human Liver Stem Cell Transplantation Alleviates Liver Fibrosis in a Rat Model of CCl 4 -Induced Liver Fibrosis
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Lee JH, Lee S, Park HJ, Kim YA, Lee SK
- KMID: 2522565
- Int J Stem Cells.
- 2021 Nov;14(4):475-484.
- doi: 10.15283/ijsc21031
Background and Objectives: Mesenchymal stem cells (MSCs) elicit therapeutic effects against liver fibrosis in animal models. Human liver stem cells (HLSCs) are cells isolated from human liver tissue that have... -
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