Allergy Asthma Immunol Res.  2015 Jan;7(1):3-13. 10.4168/aair.2015.7.1.3.

Clinical Application of Exhaled Nitric Oxide Measurements in a Korean Population

• Song WJ
• Kwon JW
• Kim EJ
• Lee SM
• Kim SH
• Lee SY
• Kim SH
• Park HW
• Chang YS
• Kim WK
• Shim JY
• Seo JH
• Kim BJ
• Kim HB
• Song DJ
• Jang GC
• Jang AS
• Park JW
• Yoon HJ
• Lee JS
• Cho SH
• Hong SJ

• KMID: 2260146
• DOI: http://doi.org/10.4168/aair.2015.7.1.3

Abstract

Nitric oxide (NO) is a biologic mediator of various physiologic functions. Recent evidence suggests the clinical utility of fractional exhaled NO (FeNO) as a biomarker for assessing asthma and other respiratory diseases. FeNO methodologies have been recently standardized by international research groups and subsequently validated in several Korean population studies. Normal ranges for FeNO have been reported for various ethnic groups, and the clinical utility has been widely evaluated in asthma and various respiratory diseases. Based on current evidence including most of Korean population data, this position paper aims to introduce the methodological considerations, and provide the guidance for the proper clinical application of FeNO measurements in Korean populations.

Keyword

Exhaled nitric oxide; reference value; guideline; position paper; asthma

MeSH Terms

Asthma
Ethnic Groups
Humans
Nitric Oxide*
Reference Values
Nitric Oxide

Figure

• 

  Figure Schematic presentation of the distribution of fractional exhaled nitric oxide levels in an adult Korean population: (A) males and (B) females. The data were obtained from the studies conducted by Jo et al.45

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